修改剂量可能导致血栓风险增加或减弱药物的效果。 3. 注意药物的相互作用(3. Be aware of drug interactions) 在使用利伐沙班期间,必须注意其他药物和补充剂对其的影响。有些药物可能会与利伐沙班产生相互作用,增加出血风险或减弱药物的效果。在开始使用新药之前,务必告知医生您目前正在使用的所有药物,包括处方药、非...
Xarelto(rivaroxaban,利伐沙班) 抗凝血剂Xarelto(rivaroxaban,利伐沙班)是一种口服Xa因子抑制剂,用于从出生至18岁以下、确诊为静脉血栓栓塞(VTE)的儿童患者,包括导管相关血栓(CRT)和脑静脉窦血栓(CVST),治疗VTE以及预防VTE复发。 Xarelto是全球用药最广泛的非维生素K拮抗剂口服抗凝剂(NOAC),目前已获批9个治疗适应症,...
【生产厂家】:拜耳Bayer 【利伐沙班Xarelto作用机制】 XARELTO是一种口服生物可利用因子Xa 抑制剂选择性阻断因子Xa的活性位点和为活性不需要辅助因子(例如抗凝血酶[抗-thrombin]III)。因子X的激活因子Xa(FXa)通过内源和外源通路在血液凝固级联反应中起中心作用。 【利伐沙班Xarelto适应证和用途]】 XARELTO一种因子Xa...
3.Silverwood,J.Bayer’s stock drops to new 18-year low after asundexian trial termination.Clinical Trials Arena.28.11.2023. 4.Biocon is the first generics company to obtain approval for diabetes drug,Liraglutide,in the U.K.Biocon Press Release.27.03.2024. 5.Henderson,L.et al.When Will Lir...
参考资料: Janssen Submits Supplemental New Drug Application (sNDA) to FDA for XARELTO® (rivaroxaban) to Prevent Venous Thromboembolism (VTE) in Acute Medically Ill Patients
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4.Biocon is the first generics company to obtain approval for diabetes drug,Liraglutide,in the U.K.Biocon Press Release.27.03.2024. 5.Henderson,L.et al.When Will Liraglutide Be Generic?MyBMI.23.01.2023. 6.Otsuka’s new formulations to offset Abilify Maintena dual patent expiry impact,says Gl...
DRUG INTERACTIONS Combined P-gp and strong CYP3A inhibitors increase exposure to rivaroxaban and may increase risk of bleeding. Combined P-gp and strong CYP3A inducers decrease exposure to rivaroxaban and may increase risk of thromboembolic events. XARELTO® should not be used in patients with CrCl...
4.Biocon is the first generics company to obtain approval for diabetes drug,Liraglutide,in the U.K.Biocon Press Release.27.03.2024. 5.Henderson,L.et al.When Will Liraglutide Be Generic?MyBMI.23.01.2023. 6.Otsuka’s new formulations to offset Abilify Maintena dual patent expiry impact,says Gl...
classified as a low-clearance drug. After intravenous administration of a 1 mg dose the elimination half-life is about 4.5 hours. After oral administration of a 10 mg dose the elimination becomes absorption rate limited with mean terminal half-lives of 7 to 11 hours. Special populations ...