XANTHINE OXIDASE INHIBITORY PROPERTIES OF 1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVESXANTHINE oxidaseMOLECULAR dynamicsTHREONINEMOLECULAR dockingURIC acidREACTIVE oxygen speciesMOLECULAR modelsMOLECULAR interactionsXanthine oxidase (XO) is a versatile metalloflavoprotein enzyme that is best known f...
To screen Vietnamese medicinal plants for xanthine oxidase (XO) inhibitory activity and to isolate XO inhibitor(s) from the most active plant. Methods The plants materials were extracted by methanol. The active plant materials were fractionated using different organic solvents, including n-hexane, ...
Xanthine oxidase inhibiting effects of noni (Morinda citrifolia) fruit juice. Phytother Res 2009;23(12):1790-1.Palu A, Deng S, West B, Jensen J. Xanthine oxidase inhibiting effects of noni (Morinda citrifolia) fruit juice. Phytother Res 2009; 23(12): 1790-1. [CrossRef]...
After purification by partitioning using hexane and chloroform purified ethanol extract ed contained flavonoids, with TPC value of 16.11 ± 0.72 (mgGAE/g) and TFC value of 36.79 ± 2.96 (mgQE/g), in the same volume (0.01 mL) has xanthine oxidase inhibitory power by 75.17% compared to 1 ...
It has effective xanthine oxidase inhibitory activity (IC50: 0.2 μM). Purpurogallin also has antioxidant and anti-inflammatory effects. 靶点活性 XO:0.2 μM 体外活性 Purpurogallin(100 μM;75-120分钟;BV2鼠微胶质细胞)通过抑制脂磷酰肌醇3激酶/Akt和丝裂原活化蛋白激酶信号通路,展现出在LPS刺激的BV...
Novel hybrid compounds containing 1,2,3-triazole and naphthalene subunits as xanthine oxidase inhibitors Article 01 August 2024 Novel peptides with xanthine oxidase inhibitory activity identified from macadamia nuts: integrated in silico and in vitro analysis Article 05 May 2022 Data availability ...
the aim of this article was to overview and select the most potent recently reported XO inhibitors and to compare their structures, mechanisms of action, potency and effectiveness of their inhibitory activity,in silicocalculated physico-chemical properties as well as predictedpharmacokineticsand toxicity....
Thirty four crude extracts of Panamanian plants, from nine species of Celastraceae and Lamiaceae, were assayed for xanthine oxidase (XO) inhibitory activity. The enzymatic activity was estimated by measuring the increase in absorbance at 290 nm due to uric acid formation. Eighty five percent of the...
J. Weight loss mediated reduction in Xanthine oxidase activity and uric acid clearance in adolescents with severe obesity. Child Obes. 12, 286–291 (2016). Article Google Scholar Nakamura, T. et al. Gastric inhibitory polypeptide receptor antagonist, SKL-14959 suppressed body weight gain on ...
2) xanthine oxidase inhibitory activity 黄嘌呤氧化酶抑制活性 例句>> 3) Xanthine/Xanthine Oxidase 黄嘌呤/黄嘌呤氧化酶4) xanthine xanthine oxidase 黄嘌呤-黄嘌呤氧化酶5) xanthine oxidase 黄嘌呤氧化酶 1. Purification of xanthine oxidase from fresh cream and its properties; 新鲜奶油中黄嘌呤...