This gene encodes a member of the Nedd4 family of E3 ligases, which play an important role in protein ubiquitination. The encoded protein contains four WW domains and may play a role in multiple processes including chondrogenesis and the regulation of oncogenic signaling pathways via interactions wi...
WWP2, a recently identified ubiquitin E3 ligase, has been proved a multifunctional gene by degradation a series of targets via ubiquitin-dependent proteasome system, including PETN, Smads, Oct4, EGR2, TIRF and so. Hereafter, we reviewed the recent research process about the function of WWP2....
Huimei Chen et al.WWP2 Regulates Kidney Fibrosis and the Metabolic Reprogramming of Profibrotic Myofibroblasts. Journal of the American Society of Nephrology, 2024, doi:10.1681/ASN.0000000000000328. Scientists discover 'powerhouse' gene, opening doors to new treatments for kidney disease https://medicalx...
Scientists discover 'powerhouse' gene, opening doors to new treatments for kidney disease https://medicalxpress.com/news/2024-03-scientists-powerhouse-gene-doors-treatments.html
使用gene ontology cc术语“细胞外基质”在字符串中注释的基因也被检索并用较厚的节点边界突出显示。[0429]1.6 dcm队列中wwp2同种型的eqtl定位[0430]wwp2同种型表达水平在dcm患者中从tophat输出与sailfish 0.6.3进行量化[42]。sailfish使用默认参数化运行。通过使用多元线性模型,针对相关技术(“rin评分”和“文库...
This gene encodes a member of the Nedd4 family of E3 ligases, which play an important role in protein ubiquitination. The encoded protein contains four WW domains and may play a role in multiple processes including chondrogenesis and the regulation of oncogenic signaling pathways via interactions wi...
Entrez-Gene Id: 11060 View in PhosphoSitePlus® 限制使用 除非CST 的合法授书代表以书面形式书行明确同意,否书以下条款适用于 CST、其关书方或分书商提供的书品。 任何书充本条款或与本条款不同的客书条款和条件,除非书 CST 的合法授书代表以书面形式书独接受, 否书均被拒书,并且无效。 专品专有“...
Ensembl Gene IDENSG00000198373.13 Ensembl mRNA IDWWP2-202 包装清单: 产品编号产品名称包装 QH33161SHuman WWP2 qPCR Primer Pair1nmol each —说明书1份 保存条件: -20℃保存。建议复溶后进行适当分装,避免反复冻融。 注意事项: PCR扩增产物的长度可能会因基因转录后存在多种剪接形式而有所差异。
The WW domain-containing protein 2 (Wwp2) gene, the host gene of miR-140, codes for the Wwp2 protein, which is an HECT-type E3 ubiquitin ligases abundantly expressed in articular cartilage. However, its function remains unclear. Here, we show that mice l
图2 WWP2对p21的表达存在负向影响Fig.2 The expression level of WWP2 gene had a negative effect on the expression of p21 2.3 CHX处理WWP2过表达及敲减细胞系 用CHX处理过表达WWP2的293T细胞0、4、8 h。如图3A所示,随着CHX作用时间延长,对照组和过表达组p21的表达水平均逐渐下降。过表达WWP2使p21的半衰期...