WU-NK-101是一款记忆天然杀伤(NK)细胞疗法。该公司同时宣布美国FDA已授予WU-NK-101用于治疗AML的孤儿药资格。 截图源自Wugen官网 WU-NK-101是利用记忆NK细胞的力量来治疗血液和实体肿瘤。记忆NK细胞是功能强劲、持久的免疫细胞，表现出增强的抗肿瘤活性和细胞因子诱导的记忆样表型。目前WU-NK-101正在开发治疗复发或...
WU-NK-101是一款记忆天然杀伤(NK)细胞疗法。该公司同时宣布美国FDA已授予WU-NK-101用于治疗AML的孤儿药资格。 截图源自Wugen官网 WU-NK-101是利用记忆NK细胞的力量来治疗血液和实体肿瘤。记忆NK细胞是功能强劲、持久的免疫细胞,表现出增强的抗肿瘤活性和细胞因子诱导的记忆样表型。目前WU-NK-101正在开发治疗复发或难...
WU-NK-101 (WUNK) is a PBMC-derived, cytokine-reprogrammed, expanded, and cryopreserved off-the-shelf memory-like (ML) NK cell product. WUNK exhibits enhanced cytotoxicity, metabolic fitness/flexibility, and resistance to tumor microenvironment (TME) immunosuppression compared to conventional NK cells...
Putative Predictors of Response to WU-NK-101, an Allogeneic, Enhanced Memory (ML) Natural Killer (NK) Cell Therapy Product, for Relapsed/Refractory (R/R) A... S Rutella,AF Cashen,J Muth,... - 《Blood》 被引量: 0发表: 2022年 195Characterization of WU-NK-101, a feeder cell-free ...
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WU-NK-101是一款记忆天然杀伤(NK)细胞疗法。该公司同时宣布美国FDA已授予WU-NK-101用于治疗AML的孤儿药资格。 截图源自Wugen官网 WU-NK-101是利用记忆NK细胞的力量来治疗血液和实体肿瘤。记忆NK细胞是功能强劲、持久的免疫细胞,表现出增强的抗肿瘤活性和细胞因子诱导的记忆样表型。目前WU-NK-101正在开发治疗复发或难...
The MonetaTM Platform is a feeder cell-free system of fusion protein complexes to generate, expand, phenotypically maintain, and cryopreserve memory NK cells for an 'off-the-shelf' allogeneic drug product. Here we define the molecular characteristics of WU-NK-101, through RNA and protein ...
Through cytokine reprogramming, NK cells can also gain memory-like features that augment their anti-tumor potential. WU-NK-101 is a cytokine-reprogrammed, expanded, cryopreserved, off-the-shelf NK cell product derived from peripheral blood mononuclear cells, with no additional engineering. Methods: ...