在施用6-OHDA之前,用三种不同剂量的WR-1065二盐酸盐(20,40和80μg/2μL/大鼠)预处理3天,显着(P <0.001)提高SOD活性并将其恢复至正常范围与6 -OHDA损伤的大鼠[3]。激酶实验对于Western分析,用1mM WR-1065二盐酸盐(WR-1065)处理细胞24小时,收获细胞的亚汇合培养物并在补充有蛋白酶抑制剂的RIPA...
WR-1065 dihydrochloride CAS号: 14653-77-1 MDL号: 分子式: C5H14N2S.HCL 分子量: 170.704 COA MSDS 大包装询价 库存状态为分装好的现货产品(1.2.3...等具体数量),每日16:00前订单当天发出; 库存状态为未分装好的现货产品(显示 “现货” 字样),每日15:00前的订单1-3个工作日发出; 若小包装产品...
产品活性:The DNA-binding activity is increased in a WR-1065 concentration-dependent manner. Cells treated with 1 mM WR-1065 dihydrochloride for 24 h revealed that all of the p53-induced genes analyzed are transactivated following WR-1065 dihydrochloride treatment, in a p53-dependent manner. Signif...
14653-77-1|氨磷汀硫醇|WR-1065 dihydrochloride,使用说明 氨磷汀硫醇用途:WR-1065 dihydrochloride 可以保护正常组织免受某些癌症药物的毒性作用,并通过 JNK 依赖性信号通路激活 。1.氨磷汀硫醇产品物理参数:2.氨磷汀硫醇技术资料:3.氨磷汀硫醇同类产品列表:4.氨磷汀硫醇生物活性:5.氨磷汀硫醇物理化学性...
In the first 24h 0/5 μM WR-1065 was added and Cyt B was added in 76h in the cells, the viability of AZT treated MOLT-3 cells did not altered. [1] Moreover, in RKO36 cell lines (derivative RKO human colorectal carcinoma carrying a GFP-pCMV-EGFP2Xho), 4 mM final concentration ...
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硫醇氨WR-1065和WR-255591对培养哺乳动物细胞的辐射防护:γ线照射后防止DNA双链断裂和细胞杀伤间的关系 哺乳动物细胞的基因组DNA可能是电离辐射的临界靶子,硫醇氨能减轻辐射对DNA的损伤程度,是其辐射防护作用的重要机制.在不同类型DNA损伤中,常把DNA双链断裂(DSBs)与细胞... 许廷贵 - 《国际放射医学核医学杂志》...
学术范收录的Journal Amifostine metabolite WR-1065 disrupts homologous recombination in mammalian cells.,目前已有全文资源,进入学术范阅读全文,查看参考文献与引证文献,参与文献内容讨论。学术范是一个在线学术交流社区,收录论文、作者、研究机构等信息,是一个
Oral administration of the PCEC/WR-1065 led to survival benefit as well as protective effects on hematopoiesis and main organs with respect to the irradiation and oral free WR-1065 groups after 7.2 and 8.0 Gy total body irradiation, respectively. In vivo biodistribution studies indicated that ...
WR-1065对不同辐射敏感性人肿瘤细胞的保护作用 目的:研究抗辐射药 WR- 10 6 5对两种不同辐射敏感性的人恶性胶质瘤细胞系的辐射防护作用。方法 :M0 5 9J和 M0 5 9K恶性胶质瘤细胞系来源于同一肿瘤标本的不同部位 ,... 刘晓秋,穆传杰 - 《国际放射医学核医学杂志》 被引量: 0发表: 2001年 WR-2721,...