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This was performed by a single observer at follow-up (JLY). Inter-observer variability between WN and JLY was evaluated by consecutive lens grading at the same slit lamp of the right eye of 25 patients with severity ranging from 2 to 6 for nuclear opacity (NO) and colour; from 0 to ...
WP1130-induced c-FLIP downregulation was regulated by microRNA (miR)-708 upregulation via inhibition of USP9X. Interestingly, knockdown of USP9X markedly induced c-FLIP downregulation, upregulation of miR-708 expression and sensitivity to TRAIL. Furthermore, ectopic expression of USP9X prevented c...