Chai, "Role of Wnt and Notch signaling in regulating hair cell regeneration in the cochlea," Frontiers of Medicine, vol. 10, no. 3, pp. 237-249, 2016.M. Waqas, S. Zhang, Z. He, M. Tang, and R. Chai, "Role of Wnt and notch signaling in regulating hair cell regeneration in ...
下面就Wnt和Notch信号通路及其在肿瘤发生发展中的交互作用以及与口腔鳞状细胞癌的关系作一综述。 【关键词】Wnt; Notch; 鳞状细胞癌; 交互作用 ACrosstalk between Wnt and Notch signaling pathways and their relationships with oral squamous cell carcinoma PANG Bao-xing, JIN Xiao-ming. (Dept. of Stomatology...
器官的稳态平衡需要对成体干细胞严格调控,并通过多种信号整合实现干细胞向终末细胞的分化。 Tian, H., et al., Opposing activities of Notch and Wnt signaling regulate intestinal stem cells and gut homeostasis. Cell Rep, 2015. 11(1): p. 33-42. 当Not...
器官的稳态平衡需要对成体干细胞严格调控,并通过多种信号整合实现干细胞向终末细胞的分化。 Tian, H., et al., Opposing activities of Notch and Wnt signaling regulate intestinal stem cells and gut homeostasis. Cell Rep, 2015. 11(1): p. 33-42. 当Notch信号受到抑制,小肠干细胞倾向于分化成分泌细胞...
Tian, H., et al., Opposing activities of Notch and Wnt signaling regulate intestinal stem cells and gut homeostasis. Cell Rep, 2015. 11(1): p. 33-42. 当Notch信号受到抑制,小肠干细胞倾向于分化成分泌细胞,并抑制营养吸收细胞的分化趋势。当Notch受体被特异性抗体阻断后,结果发现阻断Notch会解除Wnt途...
Wnt;Notch; 串话;肿瘤 doi:10.3969/j.issn.1673-2588.2010.03.016 Cross—talkbetween Wnt andNotchsignalingpathway anditsroleinthegenesisanddevelopmentoftumors ZHAOYuanyuanl,LIChunyan2 (’1.Grade2007.sewn-yearSystem;2.Third Department ofLaboratoryTechnologyCenter,ChinaMed&alUniversity,Shenyang I 10001,China...
TargetMol Wnt/Hedgehog/Notch 通路化合物库可以提供240 个 Wnt & Hedgehog & Notch 靶点相关的生物活性小分子化合物的特有集合，用于相关通路的研究及药物的筛选，可用于高通量、高内涵筛选。化合物库组成：参考文献：1.Grainger S, Willert K. Mechanisms of Wnt signaling and control. Wiley Interdiscip Rev Syst...
TargetMolWnt/Hedgehog/Notch 通路化合物库可以提供 240 个 Wnt & Hedgehog & Notch 靶点相关的生物活性小分子化合物的特有集合,用于相关通路的研究及药物的筛选,可用于高通量、高内涵筛选。 化合物库组成: 参考文献: 1. Grainger S, Willert K. Mechanisms of Wnt signaling and control.Wiley Interdiscip Rev Sy...
[关键词] Wnt信号通路; Notch信号通路; 肿瘤干细胞; 干细胞; 胚胎干细胞; 造血干细胞; 自我更新; 串话[中图分类号] R329.2;R730.23 [文献标识码] A [文章编号] 167322588(2008)0620477205RoleofWntsignalingpathwayandNotchsignalingpathwayintheself2renewaloftumorstemcellsZHANGChun2mei1,LIChun2yan2,CUIZhe2...
Science, 2011, 332(6028):458-461. [136]Kim W, Khan SK, Gvozdenovic-Jeremic J, et al. Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis[J]. J Clin Investi, 2017, 127(1):137-152. (责任编辑 狄艳红) ...