Intronic deletions in the WNK1 gene result in its overexpression and lead to pseudohypoaldosteronism type II, a disease with salt-sensitive hypertension and hyperkalemia. This review focuses on the recent evide
Gene SummaryThe WNK1 gene encodes a cytoplasmic serine-threonine kinase expressed in distal nephron.[supplied by OMIM 包装清单: 产品编号产品名称包装 L16796WNK1 Knockout Lentivirus108TU —说明书1份 保存条件: -80℃保存,至少一年有效。 注意事项: ...
This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary...
In addition, we investigated the interactions between the haplotypes of the WNK1 gene and dietary sodium and potassium intake for determining inter-individual variations in blood pressure. Our data support the hypothesis that part of the variation in blood pressure response to dietary sodium and ...
Hereditary sensory and autonomic neuropathy II due to mutation in the WNK1 gene in a Chinese family Gao Lihong Li Shanshan Fu Wenzhen Authors Info & Affiliations Published: 2016 -12 -01 · DOI: 10.3760/cma.j.issn.0578-1426.2016.12.0101275 53 0 0 1 0...
Gene SummaryThe WNK1 gene encodes a cytoplasmic serine-threonine kinase expressed in distal nephron.[supplied by OMIM 包装清单: 产品编号产品名称包装 L16797WNK1 Knockout HEK293T Cells1支/瓶 —说明书1份 保存条件: 对于细胞培养瓶或离心管运输的活细胞,室温3-5天有效;对于干冰运输的冻存细胞,液氮保存...
Gene ID (NCBI) 65125 RRID AB_2881119 偶联类型 Unconjugated 形式 Liquid 纯化方式 Antigen affinity purification UNIPROT ID Q9H4A3 储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 储存条件 Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20...
Table S4. Gene ontology analysis based on the detected 2,323 DEGs in the Wnk1f/f; Wnt7a -Cre SPCa and SPCb spermatocytes, related to Figures 4 and 5 Table S5. Ingenuity canonical pathways that were impacted in the Wnk1f/f; Wnt7a-Cre SPCa and SPCb spermatocytes based on the 2,323...
1) WNK1 gene WNK1基因 1. Results WNK1 gene was widely expressed in mouse tissues. 结果WNK1基因广泛表达在小鼠各组织中,在肾脏有9。 2. Objective This study investigated whether WNK1 gene exon13 Pro589Thr polymor- phism were associated with risk of essential hypertension. 目的探讨WNK1...
Phenomenon explanation:The possible reasons that the actual band size differs from the predicted are as follows:1.Splice variants: Alternative splicing may create different sized proteins from the same gene.2. Relative charge: The composition of amino acids may affects the charge of the protein.3....