Neural activity in the sensory cortex combines stimulus responses and ongoing activity, but it remains unclear whether these reflect the same underlying dynamics or separate processes. In the present study, we show in mice that, during wakefulness, the n
Current evidence suggests that myofascial trigger points (MTrPs) induce central sensitization in the related spinal dorsal horn, and clinical studies indicate that A fibers are associated with pain behavior. Because most of these clinical studies applied behavioral indexes, objective evidence is needed. ...
Short-chain fatty acids (SCFAs) derived from gut bacteria are associated with protective roles in diseases ranging from obesity to colorectal cancers. Intake of microbially accessible dietary fibers (prebiotics) lead to varying effects on SCFA production in human studies, and gut microbial responses to...
are organized in a domain-within-domain TAD hierarchy. Within TADs, the inner and smaller subTADs not only manifest cell-to-cell variability, but also precisely regulate transcription and differentiation. Although over 20 TAD callers are able to detect TAD, their usability in biomedicine ...
However, despite the multivalent charge presentation, not all fibers led to high levels of membrane activity and cellular uptake. The flexibility of the cationic charge domains on self-assembled nanofibers plays a key role in effective membrane perturbation. Nanofibers were found to sacrifice their ...
E: A higher magnification image of Bruch's membrane directly adjacent to the foveal pit; the elastin fibers in this region are very sparse and thin (arrow). When the extramacular EL is viewed en face (F), its porosity (asterisk) is evident. These discontinuities contribute to the integrity...
What are the Qualities of a Competent Auctioneer? Must be Confident Always in Any Auction If an auctioneer talks too quickly or appears nervous, any buyer will fail to be inspired with his/ her confidence and will most likely hold back his/ her bid. For this reason, it is recommended that...
(Para 11) What are the chances that someone would be so nice? The writer is emphasizing here that such kindness is very unusual. 4 … looking back after all these years, you only need one or two breaks in your life to succeed. (Para 13) A break here means a chance to be ...
Falls are a common cause of injury in older adults (OAs), and age-related declines across the sensory systems are associated with increased falls risk. The vestibular system is particularly important for maintaining balance and supporting safe mobility,
As a result, electric potentials are largest along the dorsal root fibers (DR-fibers, Fig. 2a), which are recruited at the lowest stimulation amplitudes (Fig. 2b). DR-fibers are followed by longitudinal fibers running in the spinocerebellar tract (ST-fibers), in the dorsal columns (DC-...