肾细胞癌 Diagnosis:Wilms' tumor 最后诊断:Wilms瘤 Discussion Wilms' tumor is the most common malignancy of the kidneys in children. The tumor can grow asymptomatically and is often identified on physical exam as an abdominal mass after significant growth. Children are usually identified with the tu...
Brzezinski J, Shuman C, Choufani S, et al. Wilms tumour in Beckwith- Wiedemann Syndrome and loss of methylation at imprinting centre 2: revisiting tumour surveillance guidelines. Eur J Hum Genet 2017; 25: 1031-1039.Brzezinski J, Shuman C, Choufani S, et al. Wilmstumour in Beckwith-...
doi:10.1002/ajmg.1320570427Andrew F. OlshanJohn Wiley & Sons, Ltd.American Journal of Medical GeneticsOlshan, A. F. (1995). Wiedemann-Beckwith syndrome, Wilm's tumor, birth weight, and insulin-like growth factor 2. Am. J. Med. Genet. 57, 640....
Beckwith-Wiedemann syndrome - 17.3%, Denys-Drash syndrome - 20%, Pearlman syndrome, as well as in familial WT - 16%.Citation10Bilaterality remains a significant clinical issue despite satisfactory treatment
The renal parenchyma should also be examined for the presence of nephrogenic rests and for indications of an underlying predisposing syndrome37. For example, patients with Denys–Drash syndrome often demonstrate diffuse mesangial glomerulosclerosis, and Beckwith–Wiedemann syndrome is associated with nephroli...
Koufos, A. et al. Familial Wiedemann-Beckwith syndrome and a second Wilms tumor locus both map to 11p15.5.Am. J. Hum. Genet.44, 711–719 (1989). CASPubMedPubMed CentralGoogle Scholar Pal, N. et al. Preferential loss of maternal alleles in sporadic Wilms’ tumour.Oncogene5, 1665–1668...
Statistically increased occurrence of BWT is observed in patients with WAGR syndrome - approximately 17%, Beckwith-Wiedemann syndrome - 17.3%, Denys-Drash syndrome - 20%, Pearlman syndrome, as well as in familial WT - 16%. 10 Bilaterality remains a significant clinical issue despite satisfactory ...
Screening for Wilms tumor in children with Beckwith-Wiedemann syndrome or idiopathic hemihypertrophy. Med Pediatr Oncol. 1999;32(3):196–200.Choyke PL, Siegel MJ, Craft AW et al. Screening for Wilms tumor in children with Beckwith- Wiedemann syndrome or idiopathic hemihypertrophy. Med Pediatr...
THE RELATIONSHIP BETWEEN NEPHROMEGALY AND WILMS TUMOR IN CHILDREN WITH BECKWITH WIEDEMANN SYNDROME. † 8491996 Abstracts The American Pediatric Society and The Society for Pediatric Researchdoi:10.1203/00006450-199604001-00871Michael DeBaunPeter Choyke...
J. Bruce Beckwith MDPaul Grundy MDJohn Wiley & Sons, Ltd.Medical and Pediatric OncologyWeksberg R, Squire JA: Molecular biology of Beckwith-Wiedemann syndrome. Med Pediatr Oncol 1996, 27 (5) : 462–9.Haber, D. A., Englert, C., Maheswaran, S. (1996) Functional properties of WT1. ...