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It is also important to note that a meta-analysis of randomized trials comparing CPA and ADT with ADT alone showed a survival decrease in the CPA group [53]. Overall, the nonsteroidal antiandrogens appear to be better tolerated than castration [54]. Agents targeting AR that are in clinical...
According to the predicted closest point of approach (CPA), TCAS produces a TA at approximately 45 seconds and an RA at 35 seconds to CPA. TCAS is designed to reduce the incidence of mid-air collisions and has been very successful since its introduction. However, the major concern with ...