The meaning of WILD TYPE is a phenotype, genotype, or gene that predominates in a natural population of organisms or strain of organisms in contrast to that of natural or laboratory mutant forms; also : an organism or strain displaying the wild type.
wild Relating to an entity, such as a virus, bacterium or gene that arises naturally or that comes from a natural environment, rather than that originates in a laboratory or as a result of artificial circumstances. Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005Want...
For example, comparing gene expression in wild-type organisms with that seen in mutants can be used to identify the targets of transcription factors or signaling pathways [1], to organize genes into modules [2–7], and to order genes in pathways [8, 9]. Recently, genome-scale tiling ...
Two hundred individuals from six river basin populations have been sampled, and their genetic structure analyzed by using 25 nuclear microsatellites loci to investigate the gene diversity of wild grape populations in Andalusia at two levels: total individuals and at river basin populations. Also, the...
Attenuated sporozoite vaccines have been produced using radiation attenuation (RA), gene modification or concomitant drug administration19. RA is the most commonly used method, whereby RA sporozoite vaccines are currently entering phase 3 clinical trials20,21. RA introduces double strand breaks in DNA22...
This review will summarize recent evidence that most, if not all, encompass at least a subpopulation of mutant , meaning characterized as wild-type are in most cases with relatively low mutant content. Recent studies support the hypothesis that relapse in advanced colorectal patients tre...
GeneWeb - Genealogy software. It comes with a Web interface and can be used off-line or as a Web service. (Demo, Source Code) GPL-2.0 OCaml Gramps Web - Web app for collaborative genealogy, based on and interoperable with Gramps, the open source genealogy desktop application. (Demo, Sour...
(Fig.2hand Supplementary Movie1, Supplementary Fig.5), most prominently in the tectum, thalamus, medial hindbrain, pallium, and tegmentum. In the hindbrain, these ROIs are concentrated in a longitudinal rostro-caudal strip along the pathway of the tectobulbar projections, meaning that they ...
Protein degraders are characterized as event-driven mechanisms, meaning that they are competent for proteolytically targeting the protein substrate, even under transient binding.25 Because PROTACs can use both the allosteric binding sites and the active sites of target proteins, they possess great ...
type ATTR-CM, because currently there is no specific test (e.g., abnormal light chains or the presence of a genetic variant in theTTRgene), which is indicative of the potential disease in order to pursue a definitive diagnosis. Furthermore, identification of wild-type ATTR-CM is important,...