Mutations in SOD1 cause amyotrophic lateral sclerosis (ALS) through gain-of-function effects, yet the mechanisms by which misfolded mutant SOD1 (mutSOD1) protein impairs human motor neurons (MNs) remain unclear. Here, we use induced-pluripotent-stem-cell-derived MNs coupled to metabolic stable ...
was identified through linkage analysis and fine mapping.54 Besides breast cancer and T2D, several other diseases have also been studied intensively in that year; the prominent ones being CD, T1D, amyo- trophic lateral sclerosis, coronary diseases, restless legs syndrome, prostate cancer and colore...
Molecular and immunological tests have been developed for leprosy diagnostics and prognostics, and among these tools, the PCR and its variations, ELISA (enzyme-linked immunosorbent assay) and other serological tests such as the lateral flow (ML-Flow) are the main technologies employed with different...
respectively9. Members of the genus are important components of alpine and temperate vegetation.Salix brachistaSchneid is a typical alpine willow mainly distributed in the subnival
Molecular and immunological tests have been developed for leprosy diagnostics and prognostics, and among these tools, the PCR and its variations, ELISA (enzyme-linked immunosorbent assay) and other serological tests such as the lateral flow (ML-Flow) are the main technologies employed with different...
It responds to various developmental and environmental events, such as embryogenesis, organogenesis, shoot elongation, tropical growth, lateral root formation, flower and fruit development, tissue and organ configuration, and vascular differentiation [1]. At the molecular level, most of these processes ...