of which 131 undergo programmedcell death. Since the entire schedule of cell division and cell death is known for this organism, it has become a favorite system for the investigation of apoptosis. – And because essentially the same process is observed in all higher organisms, the insights...
Rather than leaving a cell that is fundamentally prevented from undergoing apoptosis, very often the resulting cancer cell is quite ready to undergo apoptosis compared to normal cells. This distinction is, indeed, an important determinant of the therapeutic index for conventional chemotherapy that we ...
What would happen if they did not? Why do B-cells need helper T-cells? What are the functions of B-cells ? Why is cellular respiration important? Why are storage granules important to the cell? What are the types of B cells? Why is apoptosis important in embryonic development? Why are...
Under this hypothesis, Aβ would not be a peptide released into the cell by accident or genetic predisposition, but a specific and generalised response to foreign agents10. This “Antimicrobial Protection Hypothesis” would thus significantly change the paradigm, and identify Aβ and its aggregation...
1 Why be interested in death? Fig. 1 Cells undergo distinct morphological changes when they progress through either necrosis or apoptosis. Necrosis is characterized by cell swelling and disruption of cellular organelles. Necrotic cells lyse releasing their contents a... NJ Mccarthy...
Several studies indicate that impaired folliculogenesis and germ cell apoptosis may be the main causes of the follicular depletion in females with TS (4, 5). Owing to accelerated follicular atresia, the majority of females with TS undergo premature ovarian insufficiency before or around the time of...
While this effect on immune cells is usually undesirable, it is exactly what would be useful for activating immune cells, initiating provirus transcription in retrovirus-infected cells, and facilitating selective apoptosis of these infected cells. In general, G3139 might have benefit in clearing ...
If one assumes a higher mutational load of the smaller paternal gamete as driving force for the maternal predominance of organelle transmis- sion (as we propose here), this would be a very reasonable scenario. Most eukaryotes are unicellular and many of them are isogamous. In ...
T-lymphocytes that failed the negative selection test were not destroyed, one might predict that the person would suffer from what type of disorder?What is the function of the helper T cell? a. It produces antibodies. b....
Many neurons undergo apoptosis following injury, especially if the lesion is close to their cell bodies. Presumably, this was because axotomized neurons are deprived of the trophic support which is normally provided 819 820 Bcl-2 in the regulation of nerve regeneration DF Chen and S Tonegawa by ...