After centrifugation (2,500×g, 5 min, 22°C), undiluted plasma was removed and stored at −80°C for further analysis. Metabolic and organ injury/function parameters In the first experiment (28 day follow-up), urea nitrogen (urea), glucose, lactate dehydrogenase (LDH) and alanine ...
Explain why the enzymatic activity of creatine kinase and lactate dehydrogenase is measured indirectly using NADH and NADPH. Much of the digestive system relies on the activity of enzymes. The stomach secretions include an enzyme (pepsin)along with ...
In the process of converting pyruvate to lactate, lactate dehydrogenase consumes oxygen by oxidizing NADH to NAD+, as illustrated in the accompanying figure. So, if the bioavailability of NADH is increased, it stands to reason that the astrocyte would have an enhanced ability to convert pyruvate...
It is a bit strange that cancer cells addiction to glutamine (known since 1956) and necessity for exporting lactate (known since Warburg’s discovery 1923) has not been subject to clinical trials until 2018 with CB- 839 and AZD-3965, respectively. Clearly, there is still a lot of drug ...