Believe it or not, but the gut and the brain are closely connected. The gut-brain axis enables the communication between the gut microbiome and the brain, and this has a significant impact on mental health. Probiotics have been shown to improve mood, reduce anxiety and depression, and even ...
Polluted air and steadily rising temperatures are linked to health effects ranging from increased heart attacks and strokes to the spread of infectious diseases and psychological trauma.
Atherosclerotic cardiovascular disease is a major cause of disability and death worldwide. Most therapeutic approaches target traditional risk factors but ignore the fundamental role of the immune system. This is a huge unmet need. Recent evidence indica
Therefore, anti-inflammatory agents have been suggested as a treatment strategy for insulin resistance. This strategy has been tested in laboratory studies and clinical trials for more than 10 years; however, no significant progress has been made in any of the model systems. This status has led ...
comprehension of the molecular resistance to the generation of adhesion molecules that are involved in the transfer of inflammatory cells into the arterial wall that also induce smooth muscle cell proliferation is needed. This basic understanding is crucial to championing the use of IMA as the first...
Increased inflammation and the altered molecular innate environment in the lung is likely to cause significant functional effects on the resident cells that are the first to encounter M.tb. The alveolar macrophage is the primary niche for M.tb survival during infection, and one of the first host...
DATA SUMMARY: Most animal studies are performed acutely in young healthy animals, whereas a significant percentage of the clinical population is elderly with many secondary complications (e.g., diabetes, systemic vascular disease, high blood pressure, immune suppression, cancer). Furthermore, unlike ...
At a later phase of the disease, lung tissue lesions are unusual, presenting notably with major intra-alveolar fibrin deposition and intraluminal loose connective tissue in alveolar ducts and bronchioles. Additionally, vascular damage is significant with cytoplasmic vacuolization of the endothelium and ...
Immune System Activation:Chronic stress can cause the immune system to overreact, releasing excessive inflammatory cytokines. This response is meant to protect the body in acute situations but can cause harmful chronic inflammation when prolonged over time. ...
The Itch-Scratch Cycle and Its Effects Scratching is a natural, instinctive response to itching. It plays a major role in skin conditions like dermatitis and insect bites, where persistent itching can cause significant discomfort. However, scratching can also worsen these conditions by fueling inflamm...