doi:10.1016/j.jctube.2016.11.004Heidary, MohsenNasiri, Mohammad JavadJournal of Clinical Tuberculosis and Other Mycobacterial DiseasesHeidary M, Nasiri MJ. Why has MDR-TB prevalence increased in Iran? J. Clin Tuberculosis Mycobacterial Dis 2016;5:9.
tuberculosisHIVRifabutinantiretroviral therapytreatment outcomespharmacokinetic interactionstoxicityswitchdrug‐resistant‐TBcost effectivenessIntroductionRifabutin, a rifamycin of equivalent potency to rifampicin, has several advantages in its pharmacokinetic and toxicity profile, particularly in HIV co‐infected patients...
AI has the power to accelerate solutions to tackle global challenges and structural inequalities. But its potential to create positive human impact will depend on a responsible, purposeful and inclusive approach that focuses on creating value for all. ...
The return of old diseases is the result of the fact that microorganisms are evolving species themselves. For example, new and serious antibiotic-resistant strains of tuberculosis have recently appeared. This evolution may have been encouraged by what some authorities consider our overuse of antibiotics...
& Gori, A. T-cell exhaustion in Mycobacterium tuberculosis and nontuberculous mycobacteria infection: pathophysiology and therapeutic perspectives. Microorganisms 9, 2460 (2021). Article CAS PubMed PubMed Central Google Scholar Moldawer, L. L. & Sattler, F. R. Human immunodeficiency virus-...
Tuberculosis is a deadly and contagious disease that affects the lungs. It is caused by bacteria and can be transmitted from person to person via droplets in the atmosphere when a sick person coughs or sneezes. The most common symptoms of tuberculosis are fever, night sweats, co...
The introduction of milk testing led to the discovery of tuberculosis and brucellosis in many cow herds, resulting in (sometimes repeated) mass culls. As this was combined with a low milk price and new subsidies for beef cows, some farmers stopped having dairy cows and switched to meat ...
Considering Mycobacterium tuberculosis, why did the rates of infection by the tuberculosis bacterium increase dramatically in the 1980's? Your mutant strain of bacteria does not form a biofilm. It appears to perform chemotaxis correctly, as well as ...
You can see other evidence for this idea in things as diverse as Taye-Sachs (an adaptation to Tuberculosis), Sickle Cell Anaemia (an adaptation to Malaria), and in lactose intolerance (a failure to adapt to continuing to eat milk after infancy) and coeliac disease (ditto for grains which ...
South Africa’s tuberculosis burden is the third highest globally and is closely associated with the country’s devastating HIV epidemic. The separation of HIV and TB services in primary healthcare services in South Africa hampers TB case finding in patients who are co-infected with HIV and TB....