Plothner M, Frank M and von der Schulenburg JG. Cost analysis of whole genome sequencing in German clinical practice. Eur J Health Econ. 2017; 18:623-633.Plothner M, Frank M, vonder Schulenburg JG. Cost analy- sis of whole genome sequencing in German clinical practice [J]. Eur J ...
This economic evaluation estimates the cost-effectiveness of whole-genome sequencing compared with whole-exome sequencing and conventional testing in
Whole Genome Sequencing (WGS) is the most comprehensive test available through Baylor Genetics. It analyzes up to 98% of the human genome, detecting known and potential disease-causing variants that may not be identified on more targeted genetic testing. Additionally, WGS covers both the protein-c...
Whole-genome sequencing (WGS) is widely employed to diagnose rare [31,32,33,34,35] and undiagnosed diseases [36] and identify actionable cancer drivers and signatures. The different clinical applications and the type of analyses that are implicated in the diagnostics are shown in Fig.2. There ...
The rapid development of technologies to sequences DNA and RNA is bringing down the cost of genomic sequencing and at the same time increasing the accuracy of the outcome. It is therefore likely that DNA sequencing capacity will spread efficiently to generic routine labs, enabling a dramatic incre...
Surveillance Tuberculosis Whole-genome sequencing Introduction The vision of the End TB Strategy proposed by the World Health Organization (WHO) is a tuberculosis (TB) -free world by the year 2035 [1]. However, the emergence and wide spread of drug-resistant TB—especially multidrug-resistant TB...
Whole genome sequencing (WGS) improves Mendelian disorder diagnosis over whole exome sequencing (WES); however, additional diagnostic yields and costs remain undefined. We investigated differences between diagnostic and cost outcomes of WGS and WES in a cohort with suspected Mendelian disorders. WGS was...
Considering theclinical application, this study also analyzed the cost and time of whole-genome sequencing. On the BGI platform, the sequencing costs of whole genome sequencing are lower than that of combined chromosome microarray and exome sequencing. In addition, the analysis time is reduced to ...
Recent advances in genomics and bioinformatics, allied with reductions in the cost of next-generation sequencing, has facilitated the development of precision medicine programmes and allowed increasing numbers of solid tumours to undergo rapid whole-genome sequencing (WGS). Whilst the primary focus of ...
Whole-genome sequencing is suitable for the study of disease-specific genomic abnormalities from cfDNA. TheInvitrogen Collibri PS DNA Library Prep Kit for Illumina Systemsenables consistent and reproducible cfDNA library ...