Watch one of our videos or check out one of our written tutorials to learn more about whole genome sequence analysis and whole exome sequencing analysis.Exome Analysis Tutorial See how to align exome resequencing data from all major NGS platforms against a reference sequence with unsurpassed ease...
tumor normal analysisWhole‐Genome Sequencing (WGSBaseSpaceNext‐generation sequencing (NGS) technologies have revolutionized the biosciences and become invaluable to the discovery of gene function and its involvement in disease conditions. The fast pace of innovation in NGS technologies has enabled the ...
PacBio whole genome sequencing analysis solutions allow you to generate gold-standard reference genomes through de novo assembly, phase haplotypes and call all structural variant types.
Objectives: The objectives of this study were to identify antimicrobial resistance genotypes for Campylobacter and to evaluate the correlation between resistance phenotypes and genotypes using in vitro antimicrobial susceptibility testing and whole-genome sequencing (WGS). Methods: One hundred-fourteen Campylob...
Whole-genome sequencing is suitable for the study of disease-specific genomic abnormalities from cfDNA. TheInvitrogen Collibri PS DNA Library Prep Kit for Illumina Systemsenables consistent and reproducible cfDNA library prepar...
-genome sequencing, and genotypes have been called for each individual for each site in the genome using a standard pipeline. The data has been filtered to retain onlybi-allelicsingle nucleotide polymorphisms (SNPs), and these have been furtherthinnedto reduce the file size for this tutorial....
Exome sequencing is a targeted sequencing approach that is restricted to the protein-coding regions of genomes. The exome is estimated to encompass approximately 1% of the genome, yet contains approximately 85% of disease-causing mutations [1]. For genetic re...
However, despite the important properties of this mushroom, there is little whole genome information for R. griseocarnosa, limiting mechanistic analysis. Here, we present the whole genome de novo sequencing of R. griseocarnosa. The recent availability of several genome sequences of published fungi...
Targeting specificity has been a barrier to applying genome editing systems in functional genomics, precise medicine and plant breeding. In plants, only limited studies have used whole-genome sequencing (WGS) to test off-target effects of Cas9. The cause of numerous discovered mutations is still co...
Whole genome sequencing (WGS) improves Mendelian disorder diagnosis over whole exome sequencing (WES); however, additional diagnostic yields and costs remain undefined. We investigated differences between diagnostic and cost outcomes of WGS and WES in a cohort with suspected Mendelian disorders. WGS was...