Therefore, in this study, we conducted whole-genome resequencing of the high- and low-fecundity hybrid white goats to determine the genes associated with fertility. In this study, we selected 6 ewes from more than 150 breeding populations and divided them into high- and low-fecundity groups (...
错义突变的发生与耐药性的出现具有同时性,从而确定了耐药性相关基因。 [ Hunt P, Martinelli A, Modrzynska K, et al. Experimental evolution, genetic analysis and genome re-sequencing reveal the mutation conferring artemisinin resistance in an isogenic lineage of malaria parasites. BMC Genomics, 2010, ...
1)检测疾病样本中高风险碱基变异位点和对应的基因;2)配合大样本分析,确定孟德尔遗传疾病(Mendelian disease)相关SNP位点和基因;3)在癌症研究过程中,检测癌症样本染色体上的突变位点、结构变异、染色体拷贝数变化以及潜在的融合基因;4)用于种群遗传学的大规模样本基因组分析,检测SNP位点、LD并绘制种群图谱;5)...
www.personalbio.cn始终以“解析序列,诠释生命”作为企业理念,秉承“立足客户需要,满足个性需求”的服务宗旨,专业提供动植物基因组测序、微生物基因组测序、宏基因组测序、RNA测序、简化基因组及外显子捕获等技术服务。 动植物基因组重测序(Whole-genome resequencing of plants and animals) 基因组重测序是对已知基因组...
Alignment, summary of data production, coverage analysis 3. 3.找出SNP和基因蛋白的结构注释。SNP detection and gene/protein structure annotation 4. 4.找出插入/缺失和基因/蛋白的结构注释。 InDel detection and gene/protein structure annotation 5. 5.完整的注释:Comprehensive annotations: dbSNP, 1000 ...
Whole-genome sequencing using NGS technology delivers comprehensive genetic analysis What is whole-genome sequencing? Whole-genome sequencing (WGS) is a comprehensive method for analyzing entire genomes. Genomic information has been instrumental in identifying inherited disorders, characterizing the mutations ...
We analyze the genetic relationships by whole-genome resequencing of 36 wild mice and 36 inbred strains. All classical inbred mice cluster together distinctly from wild and wild-derived inbred mice. Using nucleotide diversity analysis, Fst, and XP-CLR, we identify 339 positively selected genes that...
Whole-genome resequencing and transcriptomic analysis to identify genes involved in leaf-color diversity in ornamental rice plants.Whole-genome resequencing and transcriptomic analysis to identify genes involved in leaf-color diversity in ornamental rice plants.doi:10.1371/journal.pone.0124071Rice...
In addition, mutual introgression within the Guizhou chicken breeds was also suggested by the results obtained from the ADMIXTURE analysis. Furthermore, the genome wide genetic differentiation analysis was carried out to detect the admixture or migrant events happening between the breeds. Consistently, ...
Genome wide variant analysis detected 1,096,419 variants which included 943,033 SNPs and 153,386 InDels. A total of 24,920 non-synonymous SNPs were identified for 11,529 identified genes. Chromosomewise distribution of uniquely mapped reads onto reference genome showed that maximum reads were ...