Whole exome sequencing is a powerful tool to investigate genetic variations underlying cancers, Mendelian diseases, and complex human disorders.
Rapid, accurate exome sequencing with the Ion AmpliSeq Exome workflow Leveraging the ultrahigh-multiplex PCR approach ofIon AmpliSeq technologyand the superior accuracy of the newIon GeneStudio S5 Systems, theIon AmpliSeq Exome RDY Kitallows for rapid, accurate...
Next-generation RNA-Seq and Exome-Seq using the Ion Proton™ Sequencer for translational oncology research Dr. Milan Radovich Department of Surgery, Indiana University Dr. Radovich presents his experience using Ion Torrent technology for whole exome sequencing in clinical research studies...
Whole Exome Sequencing (WES) uses Next Generation Sequencing methodology to provide targeted sequence information from the coding regions of the genome.
Learn about what whole exome sequencing is, why it’s important, and how it’s furthering discoveries in cancer research.
Whole-exome sequencing (WES) represents a significant breakthrough in the field of human genetics. This technology has largely contributed to the identification of new disease-causing genes and is now entering clinical laboratories. WES represents a powerful tool for diagnosis and could reduce the '...
Benefits of whole exome sequencing Using NGS technology gives researchers more comprehensive data and more discovery power than can be achieved through PCR. Since WES is targeted sequencing, it results in a more manageable data output (~5 Gb) for genotyping applications than whole genome sequencin...
Whole-exome sequencing (WES), a ground-breaking technology, has emerged as a linchpin in neurology and neurosurgery, offering a comprehensive elucidation of the genetic landscape of various neurological disorders. This transformative methodology concentrates on the exonic portions of DNA, which constitute...
Whole-exome sequencing (WES) is application of the next-generation technology to determine the variations of all coding regions, or exons, of known genes. WES provides coverage of more than 95% of the exons, which contains 85% of disease-causing mutations in Mendelian disorders and many ...
© American College of Medical Genetics and Genomics ORIGINAL RESEARCH ARTICLE Whole-exome sequencing on deceased fetuses with ultrasound anomalies: expanding our knowledge of genetic disease during fetal development Carin L. Yates, MS, Kristin G. Monaghan, PhD, Deborah Copenheaver, MS, Kyle Re...