2022年10月25日世界卫生组织首次公布威胁健康的“真菌重点病原体清单”(WHO fungal priority pathogens list,WHO FPPL),共列出19种构成公共卫生风险的真菌,世卫组织根据真菌病原体的优先级将其分为三类:严重级别组、高级别组和中级别组三个优先组。每个级别真菌病原体的排名主要是基于它们对公众健康的影响和/或出...
[2]Chiurlo M, Mastrangelo A, Ripa M, Scarpellini P. Invasive fungal infections in patients with COVID-19: a review on pathogenesis, epidemiology, clinical features, treatment, and outcomes. New Microbiol. 2021;44(2):71...
[2] Chiurlo M, Mastrangelo A, Ripa M, Scarpellini P. Invasive fungal infections in patients with COVID-19: a review on pathogenesis, epidemiology, clinical features, treatment, and outcomes. New Microbiol. 2021;44(2):71-83. [3] WHO fungal priority pathogens list to guide research, develop...
The World Health Organization (WHO) has released a fungal priority pathogen list (FPPL) to prioritize fungal pathogens based on their research and development needs and public health importance. The list categorizes 19 major invasive fungal pathogens into critical, high, and medium priority, ...
Some new fungal species are believed to have emerged due to climate change. For example,Candida auris, which is in the WHO critical priority group, is a new fungal pathogen that has emerged since 2009 and has now spread globally, with reports of infections from every continent [14].Candida ...
Here, we report the most recent data for novel antifungals from critical members of the WHO fungal pathogen priority list and contribute add-on information and nuanced perspectives. For detailed background information about the individual drugs, we refer to previous comprehensive overviews [[2], [3...
pathogen-specificindicationsandtherelevanceoftheiruseindifferentcountriesandpopulations,particularly inLMICs,wherenegativeoutcomesareamplified(2,13). Recommendation6.Throughgloballeadership,partnershipandfunding,encourageAMRRDinLMICs.Foster collaborationtostrengthenthescientificanddrugdevelopmentcommunityinLMICstosparkscientific...
faecalis as a "typical" endocarditis pathogen, regardless of the place of acquisition or the portal of entry improved the sensitivity to correctly identify definite endocarditis from 70% (modified Duke criteria) to 96% (enterococcal adjusted Duke criteria). Spellberg B, Chambers H...
[2]Chiurlo M, Mastrangelo A, Ripa M, Scarpellini P. Invasive fungal infections in patients with COVID-19: a review on pathogenesis, epidemiology, clinical features, treatment, and outcomes. New Microbiol. 2021;44(2):71-83. [3]WHO fungal priority pathogens list to guide research, development...
Whole-genome prediction of bacterial pathogenic capacity on novel bacteria using protein language models, with PathogenFinder2 Safety and Immunogenicity of Poultry Vaccine for Protecting Critically Endangered Avian Species against Highly Pathogenic Avian Influenza Virus, United States Trump administration targets...