An analogousB. dorsalis wp-mutation was developed inB. tryoniby functional knockouts of the putativeBt_wpusing the CRISPR/Cas9 system. A total of 591 embryos from the Ourimbah laboratory strain were injected using two guides with recognition sites in the first coding exon of this gene (Fig.4a...
We conducted experiments in mice to test the effects of different doses of NATTERIN using three injection methods. NATTERIN exhibited a comparable effect to the commercially available weight-loss pill Orlistat (Control: 46.24 ± 0.68 g, NATTERIN: 22.63 ± 1.63 g, Orlistat:...
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