Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression. Brain Struct Funct 2008; 213: 93–118. 52 Schmahmann JD, Pandya DN. Fiber Pathways of the Brain. Oxford University Press: New York, NY, USA, 2006. 53 Hooker CI, Knight RT....
In addition, future neuroimaging studies and research involving animal models for eating disorders should explore whether the pattern for white matter susceptibility may correspond to neurobiological factors related to axonal size, developmental patterns of myelination, and/or injury related to hyperactivity ...
Methods Mouse models Heterozygous Asc-1 knockout mice were purchased from Deltagen (B6;129P2-Slc7a10tm1Dgen/H), and bred and housed under 45–65% humidity and a 12 h light:12 h dark cycle at ambient temperature 22 ± 2 °C. Whole body knockout mice and littermate controls ...
Gene models encoding enzymes that were predicted to degrade, modify, or synthesize glycosidic bonds were annotated based on the CAZy classification scheme ( Additional file 4: Table S7) [20–22]. The number of predicted CAZymes encoded by P. carnosa P. chrysosporium and other Agaricomycotina ...
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ANOVA using general linear models (GLM) procedure was employed for testing species, tissue and species*tissue effects on structural traits of stems. Prior to analysis, data were checked for normality using a Shapiro–Wilk test and for homogeneity using Levene’s test at P < 0.05. Data ...
PMA and MedRisk scores were entered in the models in the first step to ensure results were related to white matter microstructure metrics rather than participant age at scan or medical risk. We next assessed the main effects of the white matter metrics. To determine if the number of medical...
However, no vascular risk factor was associated with the total MTA score. Table 3 Regression coefficients in linear regression models of factors associated with total MTA score Full size tableDiscussion In this study, we founded that: (1) for patients with mild to moderate AD, a lower total ...
We found that in all cases the white matter contained SOX2+ tumour cells, which upregulated SOX10 and proliferated less than their SOX10- counterparts, confirming that GSC behaviour in xenograft models reflects disease phenotypes (Fig. 2d, e and Supplementary Table 3)3. SOX2 staining was ...
Our study provided evidence to support the hypothetical progression models underlying memory dysfunction in AD cascade and underscored the importance of FW increases and DMN degeneration in early stage of memory deficit.Similar content being viewed by others Focal white matter disruptions along the ...