Minnerop M, Luders E, Specht K, Ruhlmann J, Schneider‐Gold C, Schroder R, Thompson PM, Toga AW, Klockgether T, Kornblum C. Grey and white matter loss along cerebral midline structures in myotonic dystrophy type 2. ...
White matter hyperintensities (WMHs) are commonly seen on brain MRI in older people, and result from chronic ischaemia associated with cerebral small vessel disease The histopathology of WMHs is heterogeneous, with tissue damage ranging from slight disentanglement of the matrix to varying degrees of my...
2b, c). Notably, these symptoms showed improvement following caffeine treatment (P < 0.05, P < 0.01, respectively; Fig. 2b, c). Compared with the sham group, at 7, 14, and 21 days after WMD, the white matter in the CC area and the SVZ of the HI group was lightly ...
ObjectiveTo study the association between white matter lesions (WML) in specific locations and the risk of dementia.DesignThe Rotterdam Scan Study, a
This study evaluates the role of quantitative characteristics of white matter hyperintensities (WMHs) in predicting the 1-year recurrence risk of ischemic
Likewise, those with higher homocysteine had a greater White Matter Lesion Load (Odds Ratio=5.7, 1.1009 to 29.6594; p-value<0.05). ADL Scores were however not different between them (p-value=>0.05). Conclusion : AD group had higher serum homocysteine compared to controls and also those with...
White matter lesions(WMLs) are defects of the neuronal axons where myelin is replaced by central nervous system fluid (Fig. 3).Histologically, WMLs demonstrate demyelination, axonal loss, and astrocytic gliosis. Although the pathophysiology of these brain lesions remains obscure, they have been link...
Articles https://doi.org/10.1038/s41593-018-0285-z Invasion of white matter tracts by glioma stem cells is regulated by a NOTCH1–SOX2 positive-feedback loop Jun Wang1,2,12, Sen-Lin Xu1,12, Jiang-Jie Duan1,2,12, Liang Yi3,12, Yu-Feng Guo1,2, Yu Shi1, Lin ...
The myelination pattern of specific brain regions, such as frontal cortex, may also increase susceptibility to neurodegeneration and psychiatric symptoms after TBI. White matter pathology after TBI depends on the extent and distribution of axon damage, microhemorrhages and/or neuroinflammation. TAI occurs...
alcohol addiction,alcoholism,inebriation,drunkenness- habitual intoxication; prolonged and excessive intake of alcoholic drinks leading to a breakdown in health and an addiction to alcohol such that abrupt deprivation leads to severe withdrawal symptoms ...