A predominant route of infiltration is the white matter, which consists of bundles of myelinated axons, known as tracts, and represents approximately 60% of the brain16,23. GBMs frequently develop within white matter and spread throughout the brain using myelinated fibres as scaffolds for cell...
Non-invasive in vivo structural magnetic resonance imaging (MRI) provides a means by which we can examine the regional effects of these risk polymorphisms that code for structural and protective elements of white matter, on the volume of white matter throughout the brain. Moreover, incorporating ...
Objectives: The aim of the present study was to objectively quantify the gray/white matter boundary in ASD and age-matched control subjects. If the ASD brain shows a more indistinct boundary, this could contribute to findings of cortical thickening using MRI techniques. Methods: Postmortem tissue ...
The first inclusion ROI was defined in the anterior temporal lobe and the second ROI was placed around the white matter of the anterior floor of the external/extreme capsule. Additional exclusion ROIs were used to manually remove any streamlines that did not belong to the UF. Once virtual ...
Brain imaging was acquired from the participants. Voxel-based analysis was used to investigate differences in white matter integrity derived from diffusion tensor imaging among the four groups. Two cognitive tests related to our findings were selected to confirm the related phenotypic changes. All of ...
ADC values in the cerebellum are not altered by white matter damage, but are affected by preterm birth itself.doi:10.1111/j.1469-8749.2009.03590.xANTHONY R HARTment of Neonatology Sheffield Teaching Hospital NHS Foundation Trust Sheffield UK.ELSPETH H WHITBY...
2.3.2. White matter parcellation The modifications of fixel-based metrics were calculated for the major fiber bundles in each parcellated brain region. We followed the parcellated procedure originally described by Lo et al. (2010) using the Johns Hopkins University (JHU) DTI-based white matter ...
White matter voxels contain crossing fibres, with up to 90% of voxels containing multiple distinct fibre populations in the adult brain (Behrens et al., 2007; Jeurissen et al., 2013). However, the diffusion tensor expresses a single principal direction and is unable to characterise more than ...
These can be found throughout the white matter (WM) and the deep grey matter (GM) in the brain. In CADASIL, lacunes essentially occur within the same area as WM lesions, but at a later age than WM lesions [6]. Enlarged perivascular spaces (ePVS) have recently been recognised as ...
Although research on gray matter abnormalities in OCD has seen considerable progress, the study of white matter (WM) tracts that connect the brain regions implicated in the disorder have received considerably less attention (Fontenelle et al, 2009). A careful characterization of WM abnormalities in ...