To identify the most important parameters associated with cerebral white matter hyperintensities (WMH), in consideration of potential collinearity, we used a data-driven machine-learning approach. We analysed two independent cohorts (KORA and SHIP). WMH volumes were derived from cMRI-images (FLAIR)....
IR images increased the contrast between white matter (very hypo-intense) and gliosis, and even very discrete white matter changes, almost impercep- tible and difficult to interpret on PD images, could be ascertained (Figure 3). The topographical correlation be- tween MRI and histology was ...
Z Patay - 《European Radiology》 被引量: 204发表: 2005年 Longitudinal white matter changes in frontotemporal dementia subtypes Frontotemporal dementia is a degenerative brain condition characterized by focal atrophy affecting the frontal and temporal lobes predominantly. Changes in... Bonnie,Y.,K.,.....
Ischemic stroke leads to white matter damage and neurological deficits. However, the characteristics of white matter injury and repair after stroke are unclear. Additionally, the precise molecular communications between microglia and white matter repair during the stroke rehabilitation phase remain elusive....
This study evaluates the role of quantitative characteristics of white matter hyperintensities (WMHs) in predicting the 1-year recurrence risk of ischemic
Neuro-Behet disease with demyelination and gliosis of the frontal white matter. A rare case of neuro-with diffuse demyelination and gliosis of the frontal white matter is reported clinico-pathologically. The disease began with genital ... C Yamamori,H Ishino,T Inagaki,... - 《Clinical Neurop...
A reduced FD accompanied by an increased FC can be attributed to an enlargement in the extra-axonal matrix, which can increase as a consequence of inflammation, cell injury, or gliosis in the white matter (Raffelt et al., 2017), as that occurring in white matter edema (Assaf and ...
Metabolic Syndrome (MetSd) is a cluster of vascular risk factors that may influence cerebrovascular pathology during aging. Recently, microstructural white matter (WM) changes detected by diffusion tensor imaging (DTI) and processing speed deficits have been reported in MetSd patients. We aimed to ...
Radiology 212, 770–784 (1999). 19. Zou, K. et al. Alterations of white matter integrity in adults with major depressive disorder: a magnetic resonance imaging study. J Psychiatry Neurosci 33, 525–530 (2008). 20. Zuo, N. et al. White matter abnormalities in major depression: a tract...
Magnetic resonance imaging (MRI) based diffusion tensor imaging (DTI) can assess white matter (WM) integrity through several metrics, such as fractional anisotropy (FA), axial/radial diffusivities (AxD/RD), and mode of anisotropy (MA). Standard DTI is susceptible to the effects of extracellular...