White matter disease comprises of different medical conditions that either be progressive, a form of the disease where individuals may notice their symptoms early, but the symptoms become worst as time goes on. According to recent research and review of six large prospective studies, in persons suf...
Damage to the white matter in the adult occurs with ischemia, demyelination, infection, vasculitis, and dysmyelination due to enzyme deficits. Clinically, patients with white matter disease have a variety of symptoms, and diagnosis in this group of illnesses must be based on a combination of ...
Background: The contribution of vascular pathology to the rate of progression from mild cognitive impairment (MCI) to Alzheimer’s disease (AD) remains unclear. Objective: To ascertain the relative roles of cerebral white matter disease and medial temporal atrophy (MTA) in predicting progress...
Functional changes of white matter are largely unexplored in patients with psychiatric disorders. This study examined white matter dysfunctions common in four major psychiatric disorders (including schizophrenia, major depressive disorder, bipolar disord
and neuro-Behçet disease (Fig. 20.3). In still younger patients, many genetic disorders, referred to as leukodystrophies, affect predominantly the white matter (Fig. 29.1). Abscesses often originate at the gray–white junction, but extend into the white matter (Fig. 18.8). All of the mo...
The study by researchers led by Professor John O'Brien of the Institute for Ageing and Health, Newcastle University, Newcastle, England white brain matter, have shown that changes in the white ma...
White matter (WM) degeneration has been found during the course of cognitive decline in both Alzheimer's disease (AD) and amnestic mild cognitive impairment (aMCI), however, it is unclear whether there are different WM microstructural abnormalities between two subtypes of aMCI, including single doma...
Clinical parameters such as disease duration and attack frequency were acquired for all patients. MRI scans were acquired in the interictal period. None of the subjects had white matter lesion on the conventional MRI imaging. None of the subjects suffered from depression, which was examined by ...
Introduction : Alzheimer's disease (AD) is by far the most common type of dementia worldwide. Currently, therole of vascular factors has been increasingly appreciated in pathophysiology of AD. Serum homocysteine, and white matter lesions (WMLs) are markers of vascular risk. The present study was...
Mahsa DadarLaval University Quebec QC CanadaMyrlene GeeUniveristy of Alberta Montreal QC CanadaSimon DuchesneCERVO Brain Research Centre Quebec City QC CanadaRichard CamicioliUniversity of Alberta Edmonton AB CanadaJohn Wiley & Sons, LtdAlzheimer's & Dementia...