White matter disease damages the tissue that connects parts of your brain and spinal cord that help your nerves talk to one another. High blood pressure, blood vessel inflammation, and smoking are some causes of this disease. Treatment focuses on the causes and symptoms. Managing conditions like ...
Damage to the white matter in the adult occurs with ischemia, demyelination, infection, vasculitis, and dysmyelination due to enzyme deficits. Clinically, patients with white matter disease have a variety of symptoms, and diagnosis in this group of illnesses must be based on a combination of ...
White matter (WM) diseases are characterized by progressive degeneration of axons, oligodendrocytes and myelin sheath in one specific or multiple regions of the central nervous system (CNS). From: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2021 ...
Some research using imaging studies has found abnormalities in people's white matter prior to the development of Alzheimer's disease symptoms.2 Research has also demonstrated the presence of white matter lesions prior to mild cognitive impairment, a condition that carries an increased risk for Alzheim...
The spatial pattern of white matter dysfunction in patients with major psychiatric disorders was correlated with the distributions of disease-related neurotransmitters and expression maps of specific genes. These genes were enriched in excitatory neurons and ontological terms related to synaptic function. ...
Kaczorowska M, Kuczynski D, Jurkiewicz E, Scheper GC, van der Knaap MS, Jozwiak S. Acute fright induces onset of symptoms in vanishing white matter disease: case report.Eur J Paediatr Neurol. 2006;10(4):192-19316952472PubMedGoogle Scholar ...
Vanishing white matter disease (VWMD) is one of the most prevalent inherited leukoencephalopathies, which generally presents in childhood as a progressive disorder while less beginning in adulthood. The present report describes the clinical, neuroimaging, and genetic findings of a female patient with...
The first section will discuss imaging modalities used and their application in the diagnosis and study of metabolic disease. The second section will focus on some characteristic disorders in which abnormal white matter is visualized on neuroimaging. Although not meant to be an exhaustive summary, ...
Conclusion White matter lesions, especially in the periventricular region, increase the risk of dementia in elderly people. Cerebral white matter lesions (WML) in elderly people are thought to result from small-vessel disease and are considered to be a risk factor for dementia.1 Evidence relating ...
White matter disease Introduction ID refers to a group of aetiologically diverse conditions, resulting in below average cognitive abilities. Affected individuals are typically identified in childhood due to delay in developmental milestones. A formal diagnosis of ID is made when an intelligence quotient ...