Remarkably, the cellular and molecular mechanisms that underpin white matter invasion remain almost entirely unknown. Here, we investigated the impact of the white matter microenvironment on tumour cell fate by profiling region-specific transcriptomes of GBM cells invaded into white and grey matter, ...
Multiple sclerosis (MS) is a chronic inflammatory disease in which demyelinated lesions are present both in the grey (GM) and white matter (WM) of the central nervous system. MS presents as a relapsing remitting (RRMS) or progressive disease course. Demyelinated axons can be remyelinated ...
The few cells that were tentatively identified as labeled microglia in the light microscope proved to resemble oligodendrocytes when examined in the electron microscope. In 1-渭m sections of the cortical grey matter, heavilydoi:10.1002/cne.901930309...
van Wageningen TA, Vlaar E, Kooij G, Jongenelen CAM, Geurts JJG, van Dam A-M (2019) Regulation of microglial TMEM119 and P2RY12 immu‑ noreactivity in multiple sclerosis white and grey matter lesions is depend‑ ent on their inflammatory environment. Acta Neuropathol Commun 7:206. ...
About 1,300 species of tardigrades are known to exist, and while the nearly indestructible animals may look cute and cuddly under a microscope, they are actually covered in a hard cuticle similar to many insects. Their unique mouth, known as a bucco pharyngeal apparatus, enables tardigrades to...
We are getting small white spots on finished parts. Parts come to us and appear clean. From two different customers: - who provide us with machined 6061 extrusions - we do either black or grey anodize - we have tried many cleaning options: ...
The highest T1w/T2w intensities is not in the white matter, but, instead, in grey matter regions such as the red nucleus, substantia nigra, globus pallidus and partially the dentate nucleus. This result is consistent in both the older and younger cohort. In the white matter of the corpus...
The aim of this study was to obtain information on the axonal diameters of cortico-cortical fibres in the human brain, connecting distant regions of the same hemisphere via the white matter. Samples for electron microscopy were taken from the region of the superior longitudinal fascicle and from ...
www.nature.com/scientificreports OPEN received: 07 October 2016 accepted: 05 December 2016 Published: 13 January 2017 Multimodality MRI assessment of grey and white matter injury and blood-brain barrier disruption after intracerebral haemorrhage in mice Jie Yang1,2, Qian Li2, Zhongyu Wang2,...
The grey and white matter regions of the mammalian brain consist of both neurons and neuroglial cells. Among the neuroglia, the two macroglia oligodendrocytes and astrocytes are the most abundant cell types. While the major function of oligodendrocytes i