The invention provides a new vitamin D2 compound, 1伪-hydroxy-24-epi-vitamin D2 and certain hydroxy-protected derivatives thereof. The new compound exhibits a distinctive activity pattern comprising high potency in stimulating intestinal calcium transport and little or no activity in inducing bone ...
Using this method, we obtained a sensitive and accurate measurement of 7 VD metabolites (vitamin D2, vitamin D3, 25-hydroxyvitamin D2, 25-hydroxyvitamin D3, 1,25-dihydroxyvitamin D2, 1,25-dihydroxyvitamin D3, and 1,24,25-trihydroxyvitamin D3) for the VD metabolic pathway in different ...
The process described in the present invention is characterised in that it consists in subjecting a 5,7-diene steroid having the formula: <IMAGE> to the following stages: a. Irradiation with ultraviolet light to obtain the corresponding previtamin D; b. Isomerisation of previtamin D in an ine...
The invention provides a new vitamin D2 compound, 1伪-hydroxy-24-epi-vitamin D2 and certain hydroxy-protected derivatives thereof. The new compound exhibits a distinctive activity pattern comprising high potency in stimulating intestinal calcium transport and little or no activity in inducing bone ...
A process for the preparation of such derivatives is also provided as are certain intermediates in such process. The invention provides 1alpha,25-dihydroxyvitamin D2 derivatives and acylates thereof, which find ready application as substitutes for vitamin D3 or D2 or various of the known vitamin...
PURPOSE: To obtain vitamin D2 compounds useful as food supplement and medicament with an effective and simplified procedure by condensing steroidaldehyde with arylsulphone, followed by reduction and transformation.ヘクター エフ. デルーカハインリツヒ ケー. シユノーズ...
Novel vitamin D derivatives, analogs of vitamin D2 compounds which lack the 24-methyl substituent and are identified as 1α-hydroxy-28-norvitamin D2 and 1α,25-dihydroxy-28-norvitamin D2. The compounds of the invention are characterized by unexpectedly high vitamin D-like activity as well ...
At medicine movement of steady state at least 7 days, although the serum level in the person is continued in the density of 30ng/mL - 200ng/mL 25 hydroxy vitamin D of the sufficient single time medicinal quantity or the one hydrate and, pharmacy ideal oral carrier system and, it makes ...
Novel vitamin D derivatives, analogs of vitamin D2 compounds which lack the 24-methyl substituent and are identified as 1α-hydroxy-28-norvitamin D2 and 1α,25-dihydroxy-28-norvitamin D2. The compounds of the invention are characterized by unexpectedly high vitamin D-like activity as well ...
Use of these derivatives of vitamin D2 for the treatment or prophylaxis of various pathological conditions, especially for calcium and phosphorus imbalances and as substitutes of vitamin D3 and of its metabolites in their various applications.LUCA HECTOR F DESCHNOES HEINRICH KMORZYCKI JACEK W...