Based on several characteristic features, the hLH-R has been assigned to the δ-group of the rhodopsin family of G-protein-coupled receptors (GPCRs)10 and belongs to the glycoprotein hormone receptor cluster, together with the hFSH-R and thyroid-stimulating hormone receptor (TSH-R). Whereas mo...
New monoclonal thyroid stimulus or the inhibition antibody, the peptide array which is suitable to the variable field, and those uses in the medicine for diagnosis, the medicine for prevention and the medicine for remedyMonoclonal antibodies (mAbs) having thyroid stimulating activity (TSAb), ...
Mechanisms for high sensitivity in the assay of thyroid stimulating antibody under low salt (NaCl-deprived) hypotonic condition were analyzed using FRTL-5 rat thyroid cells. First, intracellular and extracellular cAMP contents after stimulations with TSH and Graves' immunoglobulin (Ig) were measured un...
BRAFV600E mutation can also be detected with high specificity and sensitivity by immunochemistry using anti-VE1 antibody, which stains only mutated BRAF V600E protein [8]. Detection of BRAFV600 mutation in circulating DNA is a method that is still under evaluation [9]. 4. Therapeutic options...
In particular, belzutifan, ciforadenant (CPI-444), and talazoparib achieved encouraging objective response rates (ORR) in phase I/II trials.
In the study, waist circumference, BMI, and Ferriman-Gallwey score were quantified, and plasma glucose, lipid profile, oestradiol, progesterone, total testosterone, prolactin, insulin, dehydroepiandrosterone sulphate (DHEA-S), follicle-stimulating hormone (FSH), luteinizing hormone (LH), thyroid-...
Immune System & Immune Response from Chapter 5 / Lesson 1 49K The immune system is responsible for identifying and destroying foreign matter, protecting the body from harm. Learn the details of immunology and the features of ...
Thyroid hormone receptors promote metastasis of human hepatoma cells via regulation of TRAIL. Cell Death Differ 2012; 19: 1802–1814. 13. Kaminskyy VO, Surova OV, Vaculova A, Zhivotovsky B. Combined inhibition of DNA methyltransferase and histone deacetylase restores caspase-8 expression and ...
Horseradish-peroxidase-conjugated anti-rabbit IgG (1:20,000, SA00001-2, Proteintech, Rosemont, IL, USA) was used as a second antibody. Immunoreactivity was visualized with Clarity Western ECL Substrate (Bio-Rad Laboratories, Hercules, CA, USA). The signals were detected with the UVP ChemStudio...
Most of the variants which influenced both GWG and BMI (p-value < 1E−05) were eQTLs associated with the expression of 13 genes (LRRFIP2, MLH1, GOLGA4, CCL26, RHBDD2, AC004980, POR, CCL26, GTF2IRD2, UPK3B, ART2P, LINC00974, KTP15, KRT17) in 14 tis- sues (Thyroid...