AICARFT is a folate dependent catalytic site within the ATIC gene, part of the purine biosynthetic pathway, a pathway frequently upregulated in cancers. LSN3213128 is a potent (16 nM) anti-folate inhibitor of AICARFT and selective relative to TS, SHMT1, MTHFD1, MTHFD2 and MTHFD2L. Inc...
Which of the following is the most individualizing piece of evidence? a. mitochondria DNA b. red cell serological markers c. genomic DNA d. Y-chromosome DNA Mitochondria: It is self duplicating organelle with four subcompart...
The exchange of knowledge between statisticians developing new methodology and clinicians, reviewers or authors applying them is fundamental. This is specifically true for clinical trials with time-to-event endpoints. Thereby, one of the most commonly ar
Ask a question Search AnswersLearn more about this topic: Mitosis Phases in Order | What Are the Stages of Mitosis? from Chapter 8 / Lesson 7 140K Stages of Mitosis. Learn about the steps of mitosis, including what occurs in the cell at each stage and the main differences between mi...
<p>To determine which of the following pairs is incorrectly matched, we will analyze each option one by one.</p><p>1. <strong>Option (a): sry gene - X chromosome</strong> - The SRY (Sex-determining Region Y) gene is responsible for the development of