What is the nucleophilic site in the following molecule? H_2N-CH_3 A: Oxygen. B: Nitrogen. C: Carbon. Which of these compounds is a tertiary amide? Classify each of the following as either an electrophile or a nucleophile 1. NH3 2. HO- 3. H2O 4. H3O+ 5. CH3Br ...
The present invention relates to an amide derivative of the general formula I, in which the individual substituents have specific meanings. These compounds inhibit action of phosphodiesterases. The invention also relates to a pharmaceutical composition in which said amide derivative is comprised as activ...
Chirality is a property of a molecule that is dependent on the 3D structure of the molecule. A chiral center is generally a carbon atom that has 4 different substituents and therefore the 3D orientation of those substituents affects the geometry of the atom. A chiral molecule is a molecule ...
Thereby, selective SARS-CoV-2 Mpro inhibition represents an attractive approach to COVID-19 treatment that could avoid unintended drug-target interactions. Furthermore, the antiviral efficacy of small molecule Mpro inhibitors is not expected to be affected by spike protein variants, as the SARS-...
The covalent bond between the drug and the carrier preferably is an amide bond, which bond may survive the conditions in the stomach. Thus, the prodrug may be ingested and will not be hydrolyzed completely into the carrier molecule and drug molecule in the stomach.SHASHOA UIKUTAA II...
A coenzyme is defined as an organic molecule that binds to the active sites of certain enzymes to assist in the catalysis of a reaction. More specifically, coenzymes can function asintermediate carriers of electrons during these reactions or be transferred between enzymes as functional groups. ...
Name an organic compound with a single bond. What is the functional group in the molecule below? A) amine B) alkene c) aldehyde D) aromatic E) anhydride F) carboxylic acid G) alcohol H) ketone I) ether J) amide K) alkyne L) ester ...
Is the following compound aromatic, anti-aromatic, or non-aromatic? Assume all molecules are planar.Explain the difference between an aromatic compound and an anti-aromatic compound.Define and give an example of an aromatic molecule.What is the correct assignment of the names of the following ...
q is the number 1, 2 or 3, preferably 1 or 2; if WL is present in the molecule twice or three times, it can have different meanings within the specified meaning; L is an oxygen atom or the carbonyloxy group of the formula --CO--O--, the group L and the nitrogen atom being ...
2. The altered antibody molecule of claim 1, made by recombinant DNA technology. 3. The altered antibody molecule of claim 1, which is a complete antibody molecule, an Fab fragment or an F(ab')2 fragment. 4. The altered antibody molecule of any one of claims 1 to 3, wherein the...