It is an inherent substance in animals. It has a large content in bone marrow hematopoietic tissue. It may be one of the hematopoietic factors in vivo. It can promote leukocyte proliferation and resist radiation. indication It is used to treat leukopenia caused by various reasons. Usage and do...
GM-CSF is a cytokine that increases complement- and antibody-mediated phagocytosis, enhances leukocyte chemotaxis, and augments antitumor immunity in macrophages. The lung produces GM-CSF constitutively and epithelial lining fluid in the alveolar spaces contains an approximately 100-fold higher concentration...
Scharsack JP, Steinhagen D, Kleczka C, Schmidt JO, Korting W, Michael RD, Leibold W, Schuberth HJ (2003) The haemoflagellate Trypanoplasma borreli induces the pro- duction of nitric oxide, which is associated with modula- tion of carp (Cyprinus carpio L.) leukocyte functions. Fish ...
1. An inhibitor which is deactivatable by a reagent produced by a target cell comprising: (a) a first moiety that binds, inhibits, suppresses, neutralizes, or decreases activity of a biologically active agent wherein said first moiety is operably linked to; (b) a second moiety specifically...
1994: Ligation of N-acetylgalactosamine-containing structures on rat bone marrow cells enhances myeloid differentiation and murine granulocyte-macrophage colony-stimulating factor-induced proliferation Journal of Leukocyte Biology 55(1): 127-132 Desimone, S.K.; Paisley, T.; Klisch, G.; Leeanansaksiri...
LaForce et al., “Inhibition of leukocyte candidacidal activity by serum from patients with disseminated candidiasis.” J. Lab. Clin. Med., 86: 657-666; 1975. Lazar et al., “Transforming growth factor &agr : Mutation of aspartic acid 47 and leucine 48 results in different biological acti...
W. Kincade, Characterization of murine bone marrow and spleen derived stromal cells: Analysis of leukocyte marker and growth factor mRNA transcript levels, Blood 74:303 (1989). PubMed CAS Google Scholar J. R. Sanes, J. L. R. Rubenstein, and J-F. Nicols, Use of a recombinant retrovirus...
granulocyte-myeloid-derived suppressive cells; t-SNE, t-distributed stochastic neighbor embedding. Values are standardized and expressed as median values. Statistical analyses were performed using pairedt-tests. Values ofp<0.05 (*),p<0.01 (**),p<0.001 (***), andp<0.0001 (***) were considered...
Lipidomic evidence that lowering the typical dietary palmitate to oleate ratio in humans decreases the leukocyte production of proinflammatory cytokines and muscle expression of redox-sensitive genes. J. Nutr. Biochem. 2015, 26, 1599–1606. [Google Scholar] [CrossRef] [PubMed] [Green Version] ...