Results revealed a positive correlation between MPPS and SDS scores. The younger generation showed higher mean values for MPPS and SDS, except for ON VIG. No significant generational differences were found in w
Overexpression of RAB7, which is required for the formation of endolysosomes, strongly increased tau aggregation. Conversely, inhibition of lysosomal function with alkalinizing agents, or by knocking-down RAB7, decreased tau aggregation. Together, we conclude that the enzymatic activities of lysosomes ...
Rao VB, Mitchell MS (2001) The N-terminal ATPase site in the large terminase protein gp17 is critically required for DNA packaging in bacteriophage T4. J Mol Biol 314:401–411 Article PubMed CAS Google Scholar Wu H, Sampson L, Parr R, Casjens S (2002) The DNA site utilized by bact...
The intestinal epithelium is more than just a physical barrier responsible for nutrient uptake; rather, it plays a critical role in homeostasis through its intrinsic, innate immune functions and maintains, under ideal circumstances, mutualistic and symbiotic relationships with a diverse and dynamic commun...
And, when I tried to check the technical setting of the field, it is getting redirected to a Characteristic. How to update this manually changed value into table? Please let me know if my query wasn't clear or if any other inputs required. Thank you, Vijay Krishna G. cg02 ...
Although p62 lacks a known ubiquitination domain, it contains the UBA (Ub association) domain and, thus, has been suggested to act as a receptor that delivers ubiquitinated proteins to the proteasome41. To determine whether p62 is required for Ub-dependent degradation of N-end rule substrates,...
The 2-D pattern of the DIM proteins of the plasma membrane is shown in Figure 7b. Gβ1 and 2 were the major molecules easily recognized by protein staining in 2-D gel. Because actin was polymerized in the low ionic lysis buffer containing Ca2+, which is required for plasma membrane ...
Survivin is a protein that is normally present only in G2 and M-phases in somatic cells, however, in cancer cells, it is expressed throughout the cell cycle. A prosurvival factor, survivin is both an inhibitor of apoptosis and an essential mitotic protein, thus it has attracted much attent...
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Fig. 1: Mff is required for MAVS-mediated antiviral signaling. Full size image Mff mediates MAVS cluster formation on mitochondria Fig. 2: Mff regulates accumulated distribution of MAVS on mitochondria. Full size image Mff regulates antiviral response independent of fission ...