Its functions have been proposed as involved in coordination of autonomic functions and homeostasis, including feeding, blood pressure regulation, neuroendocrine regulation, thermoregulation, and the sleep-wake cycle. Hcrt now appears to be the gene for narcolepsy. Its link to the aging nervous system...
we used two types of preclinical mouse models of pathologic pain: peripheral nerve constriction-induced neuropathic pain, using the PSNL method of nerve constriction injury38,39, and a bone cancer pain model that relies on the implantation of mouse lung carcinoma ...