The present invention relates to methods of treating proliferative disorders, particularly immunoproliferative and autoimmune disorders, and methods of producing antibodies which bind NK cell receptors for use in therapeutic strategies for treating such disorders, particularly to deplete cells involved in the...
(a) punches holes in the cell walls and membranes (b) suppresses the inflammatory response (c) causes the production of antibodies (d) stimulates toxins release to kill the cells.Cytotoxic T cells kill infected body cells by a) using perforins...
The invention relates to antibodies for inducing cell death by the specific binding of ROR1, domains thereof or nucleotide molecules encoding ROR1. There are also provided methods involving and uses of the antibodies of the invention. I Teige - WO 被引量: 13发表: 0年 Abstract 2701: RORα ...
In cell lines where either trastuzumab or pertzumab were activity these novel erbB2 antibodies showed equivalent or greater potency. Short-term experiments (1h) have shown that these novel erbB2 antibodies inhibit heterodimer formation and phosphorylation of erbB2 and AKT as well as inducing ...
Hypoxia and oxidative stress are both a cause and consequence of alterations in cellular metabolism. Cell Signaling Technology is proud to offer antibodies to investigate key biomarkers of hypoxia and oxidative stress. Available products can be accessed directly from theCST Hypoxia Interactive Signaling ...
Blood Groups & Transfusions: Blood groups are based on the antigens present on the red blood cell of an individual. Antigens on the red blood cell surface can be recognized by a person's immune system. If an antigen is identified as foreign by the i...
Monoclonal antibodies body, which a structure, which the human - interleukin - 2 (tcgf) and the light chain (lambda) of human immunoglobulin, and - - hybridoma cell lines which produce these monoclonal antibodies body 来自 掌桥科研 喜欢 0 阅读量: 12 申请(专利)号: DE19833329449 申请日期:...
Studies have been initiated to identify various cell surface and matrix components of normal human skin through the production and characterization of murine monoclonal antibodies. One such antibody, termed PG-4, identifies both cell surface and matrix antigens in extracts of human foetal and adult ...
An appropriate concentration of these ions within the cell is crucial for the functioning of proteins, whereas an overly high or low concentration of either ion is a powerful stressor to the cell [1]. Thus, all living cells are critically dependent on homeostatic mechanisms that regulate ...
Western blots of whole cell lysates using antibodies that specifically recognize ERM proteins phosphorylated near their C-terminus (T567, T564, and T558 on ezrin, radixin, and moesin, respectively) show a dominant cpERM band in resting PBT cells at about 78 kDa, consistent with moesin. ...