Hence, we show that microglia in the GBM microenvironment assist GBM cells to repair radiation induced DNA damage by secreting acetylated amino acids which are consumed by GBM cells and used to fuel the TCA cycle allowing utilization of glucose for nucleotide synthesis, thereby making the GBM ...
Reaction mixes were evaluated for percent conversion of chloramphenicol to acetylated forms, at different time points, by thin layer chromatography. Experiments were done in the linear range of the assay, and were repeated three to five times with different batches of purified DNA. Extracts from ...
Preferred compounds include the phosphoric acids where x is 0, 1 or 2 (C3, 4 and 5, respectively) as well as disodium 3-sulpho-propionate (Is63) and its free acid, and 3-borono-propionic acid (Is62). The compounds of formula (E) are N-acylated amino acids or polycarboxylic acids...
This invention- relates to the manufacture of amides of aliphatic-aromatic acids in which there is an amine residue as a substituent at the amide-nitrogen. These new amides have valuable therapeutic properties, and approximate the atropine in value. The new amides may be made either by causing....
Bacterial alginates are partly acetylated, and such modified residues cannot be epimerized. Based on a detailed computer-assisted analysis and experimental studies another PsmE region, designated N, was found to encode an acetylhydrolase. By the combined action of N and A PsmE was capable of ...