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The inscription has been said to indicate the location of The Holy Grail.Nicolas Poussin was believed to be a Grand Master of the Knights Templar, an order which captured Jerusalem during the Crusades and were known as the keepers of The Holy Grail.Chief among these is the belief that the ...
However despite this scenario, since 2000 only three new classes of antibiotics have been introduced to the market for human use and one of those is limited to topical use (Figure1) [5]. ‘Innovation gap’ is the expression that has been used to describe the lack of novel structural classe...
Those authors also did not find a mediating effect of physical activity. Exposure to greenness was measured by remote sensing data used to determine and objectively measure the degree of greenness within a given area. This information does not measure presence or access to recreational space or ...
The compound binds the ATP pocket of MET kinase in a DFG-in conformation, forming classical hydrogen bonds (Hb) with hinge region residues [99]; in addition, its phenyl ring forms a π-π interaction with the activation loop (A-loop). Ironically, the drug was found to have off-target ...