The completely new aspect was the binding of one component in the test system, here the unlabeled AuAg antibody, by simple adsorption to a surface (solid-phase), and then allowing the analyte in the patient serum, here the AuAg, to specifically bind to that coated surface. The specific bi...
A way had been found to recognize infectious blood donations and to sort them out. Blumberg used the agar gel double diffusion developed by Ouchterlony in the discovery of AuAg. Compared to the biochemical methods of protein determination, the Ouchterlony method was fairly sensitive and specific...