The goal of this review is to summarize studies in which concentrations of circulating endocannabinoids in humans have been examined in relationship to physiological measurements and pathological status. The roles of endocannabinoids in the regulation of energy intake and storage have been well studied an...
The cerebellum consists of two major parts: the deep cerebellar nuclei, from which originate the output of the cerebellum, and the cerebellar cortex. The cerebellar cortex is organized into three layers: the molecular layer, the Purkinje cell layer, which is the output layer, and the granule ce...
Candice Carty-Williams' popular and critically lauded novel Queenie came to TV this year, produced by Channel 4 and launched on Hulu in the U.S. with Disney's Onyx Collective. Dionne Brown is sublime as the titular protagonist Queenie Jenkins, a 25-year-old Jamaican British woman who's ...
L-theanine also increases the production ofGABA. GABA being;Gamma-Aminobutyric Acid. GABA has a calming effect on your body by blocking or inhibiting brain signals that would normally be triggering fear or stress. If you choose a tea that is rich in Theanine, this may help you feel less st...
Valerian root acts not only on GABA receptors but also upon adenosine receptors –these are the same receptors that caffeine binds to in the brain, but instead of blocking those receptors as caffeine would, valerian root activates them, helping one to fall asleep. Chamomile tea is readily ...
Another tale is more rooted in history than mythology. In the Tang and Song dynasties, the tribute teas of the day were produced in compressed ‘cake’ forms- not unlike the Pu-er bing of today- known as Long Feng Tuan or Dragon and Phoenix Bundle. ...
It will always be caused by persistent gastrointestinal diseases that could result in metal losses, malabsorption, or both. IDA is frequently the result of persistent intestinal loss of blood due to esophagitis, gastritis, ulcer, a cancerous colon, pre-malignant polyps, or angiodysplasia. We have...
Since these antibodies are also produced in response to vaccination, the incidence of such events following COVID-19 vaccines may not be unlikely. Nueromyelitis optica NMO is an autoimmune disorder in connection with optic neuritis and TM. NMO is mostly triggered by IgG autoantibodies against ...
Central mechanisms of anti-obesity drugs. AGRP, agouti-related peptide; ARC, arcuate nucleus; CART, cocaine- and amphetamine-regulated transcript; DAT, dopamine active transporter; D1R, dopamine 1-class receptor; D2R, dopamine 2-class receptor; GABA, gamma-aminobutyric acid; GABAAR, γ-aminobutyric...
Aβ is produced through sequential cleavage of amyloid precur- sor protein (APP) by secretases. Cleavage by β-secretase removes the N-terminal ectodomain, leaving a 99 residue C-terminal fragment (CTF) containing Aβ [3–5]. The CTF is then processed by γ-secretase [6] to produce Aβ...