Removing snow and ice from parking lots and parkades is easy, but getting the job done without damaging the deck takes some know-how. Read more February 14, 2019 Innovation, Sustainability Nobel-winning chemist makes world a better place-one enzyme at a time Frances Arnold speaks to BASF...
Angiotensin-Converting Enzyme InhibitorsBlood PressureHypertensionAdultPractice Guidelines as TopicStrokeIn June 2006, the National Institute for Health and Clinical Excellence (NICE) updated its recommendations on the management of patients with hypertension (published in 2004), in light of "significant new...
Renin converts angiotensinogen, which is produced in the liver, to thehormone angiotensin I. An enzyme known as ACE or angiotensin-converting enzyme found in the lungs metabolizes angiotensin I into angiotensin II. Angiotensin II causes blood vessels to constrict and blood pressure to increase. Wha...
One of the significant drawbacks of short-read sequencing is that it produces short fragments that lack the sequence diversity of larger DNA fragments. For this data to be useful, these fragments have to be pieced together to reassemble the original DNA sequence. This is no small task, particul...
One excellent example of successful drug development from a component of snake venom (Bothrops jararaca [Wied 1824]) is that of the inhibitors of angiotensin-converting enzyme (ACE). This enzyme is responsible for converting an inactive precursor into the locally active hormone angiotensin, which cau...
The entry of SARS-CoV-2 to the host cells via binding with ACE2 enzyme leads to ACE2 down-regulation. As a result, angiotensin II is produced excessively by the correlated enzyme ACE1, while a lower amount of ACE2 is not capable of transforming it to the vasodilator heptapeptide angiotensi...
This is partly because the protein that enables SARS−COV-2 entry into the cell, angiotensin−COnverting enzyme 2 (ACE 2), is widely distributed in the testis, including spermatogonia, the Leydig and Sertoli cells. Hikemet et al., reported that amongst over 150 investigated cell types, ...
The goal of this review is to summarize studies in which concentrations of circulating endocannabinoids in humans have been examined in relationship to physiological measurements and pathological status. The roles of endocannabinoids in the regulation of
Which COX enzyme is naproxen and diclofenac more selective for? a. COX-1 b. COX-2 c. They are equally selective for COX-1 and COX-2. Pick out the bronchodilator drug belonging to sympathomimetics: a) Isoprenaline b) Ephedrine c) Atropine d) Salbutamol ...
ACE = angiotensin-converting enzyme; BPH = benign prostatic hyperplasia; LUTS = lower urinary tract symptoms; OR = odds ratio; SNP = single-nucleotide polymorphism; VDR = vitamin D receptor. 3. Epidemiological approaches: GWAS and Mendelian randomization studies Four GWAS and two Mendelian randomizat...