Experiments that stimulated two connected neurons with varying interstimulus asynchrony confirmed the importance of temporal precedence implicit in Hebb's principle: the presynaptic neuron has to fire just before the postsynaptic neuron for the synapse to be potentiated.[10] In addition, it ha...
Peculiar synapses with a giant presynaptic bouton possessing, on average, 25 active zones. These synapses occur in the hippocampus between dentate granule cells and CA3 pyramidal neurons as well as in the cerebellum, where inputs from several brain regions synapse onto granule cells. ...
. Furthermore, CHE increased neuronal cell differentiation, neurite length, and synapse formation in the mouse hippocampus. CHE significantly enhanced learning and memory.. These results suggest that CHE is useful for improving memory function via its action in upregulating NGF.” This translates to ...
Alfsen A, Yu H, Magerus-Chatinet A, Schmitt A, Bomsel M: HIV-1-infected blood mononuclear cells form an integrin- and agrin-dependent viral synapse to induce efficient HIV-1 transcytosis across epithelial cell monolayer. Mol Biol Cell. 2005, 16: 4267-4279. 10.1091/mbc.E05-03-0192. Pub...
Functional analysis of the guanylate kinase-like domain in the synapse-associated protein SAP97 Eur. J. Biochem., 252 (1998), pp. 305-313 Google Scholar Low et al., 1996 S.H. Low, S.J. Chapin, T. Weimbs, L.G. Komuves, M.K. Bennett, K.E. Mostov Differential localization of sy...
reported that culture media supplemented with decellularized retinal RPE and RPE-conditioned media significantly increased the generation of rod photoreceptors, while the addition of decellularized NR and RPE significantly enhanced ribbon synapse marker expression and the light responsiveness of retinal organoid...