The window of opportunity is closed with the rise of CDK activity, but replication initiation can only occur, when DDK-activity is present. In a DDK- and CDK-dependent process, additional complexes bind to origins to form the pre-initiation (pre-IC) complex. This includes the Cdc45 (45),...
21 and 22) also occur in cytosolic complexes, as was observed for STAT3 (Figs. Figure 3, Figure 4, Figure 5, Figure 6, Figure 7), Western blots of Superose-6 elution fractions derived from the 100,000 ×g cytosol from Hep3B cells (no IL-6 treatment) were re-probed using anti-...
The fragmentation of legal authority to manage non-point pollution stymied effective approaches for its management [8,9,10]. Voluntary, participatory, and collaborative multi-sector partnerships were proposed to address failures in effective environmental regulation. For example, in the Clinton ...