CD22 is a sialic acid adhesin family member which regulates B-cell activation [39] (Fig.2). It is expressed only in B cell lineages except for plasma cells in normal tissues. It is expressed in most B lymphoma cells and has become a popular therapeutic target for the disease. In a pha...
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Upon reaching a recipient cell, exosomes can be internalized via endocytosis, direct fusion with the plasma membrane, or interaction with cell-surface receptors, triggering intracellular signaling pathways [15]. Endocytosis, where cells engulf extracellular material via the plasma membrane, is the ...
Specialized granule cells called juxtaglomerular cells or JG cells in the afferent arteriolerelease renin into the circulation. Renin is a proteolytic enzyme that converts an inactive plasma protein, an α2globulin, called angiotensinogen, into angiotensin I....
Malignant lymphomas comprise over 60 different neoplastic disorders that originate from lymphoid cells. The different lymphoma subtypes can be distinguished based on a combination of histological, immunophenotypic, genetic and clinical features. Malignan
stem cells What do plasma cells secrete? In adults, red blood cells are made in one place, spend most of their lifespan in another, and most are finally destroyed in yet another place. Which choice lists these locations in the correct chronological order? A. bone marrow; blood vessels; ...
Upon localization in this new site, the newly mature and permissive DCs are capable of transferring the virus to other cells [94]. In summary, there is still certainly a long way to go before we can fully understand the pathogenesis of HCMV infection, but the aforementioned mec...
The viral proteins are assembled at the surfaces of the ER membrane along with the genomic RNA, thus, constituting a mature virion that is enclosed in the vesicles at the ERGIC face of the Golgi complex. The vesicles enclosing viral particles are fused with the internal plasma membrane, bud ...
contrast, HBV is extremely infectious for humans if it enters the blood stream as has been observed in many outbreaks of the disease. Lewellys Barker and Roderick Murray studied the infectivity of plasma from an acute hepatitis B case systematically by injecting 1 ml dilutions of this plasma ...
[141,142]. Since graphene is impermeable to water, nanoscale pores could be created onto graphene by oxygen plasma or ion bombardment to prepare nanoporous graphene [96,97,143,144] (Fig.1d(VII)). Nanoporous graphene is ideal for desalination because of its one-atomic ultra-thin thickness, ...