The FDA also was very supportive of our request to move to a first-line treatment. From the outset, we have been working closely with them to ensure the CRDF-004 trial, and subsequent data, are sufficient to put us in a position for a Phase 3 trial that could lead to an...
Early on in the BDC-1001 preclinical study, researchers tested two agonists, CL264 and T785, and found that agonist potency affected the efficacy of ISAC. According to the results, CL264-ISAC was more potent than T785-ISAC in inducing myeloid APC activation and antitumor activity in vivo, ...
We found an overall lack of HIF-2α protein expression, which was confirmed in large tumor sections. HIF-1α protein was strongly expressed in most tumors, frequently adjacent to necrotic regions. In concordance, cultured SCLC but not non–small cell lung carcinoma cells showed no or extremely...
Josephine Baker was born an African-American in a deeply bigoted country in 1906. She found her way to France, where she became a popular and famous dancer, finding the fame and recognition she felt she would never find in America because of segregation to varying degrees across the whole ...
Huey Percy Newton was born in Monroe, Louisiana, on February 17, 1942. After he graduated with his associate's degree, he became more disgruntled with the Civil Rights Movement and went on to co-found the Black Panther Part...