NeurodegenerationAlthough it usually affects people in middle age, the inherited neurodegenerative condition can also develop in children and teenagers.doi:10.1038/d41586-018-05178-xDolgin ElieNature
People with Huntington's disease (HD) commonly report difficulty carrying out two everyday tasks simultaneously. This difficulty, confirmed by experimental studies, is typically ascribed to impaired attention. Yet, dual-task problems extend to relatively simple tasks, such as walking and talking, which...
and the patient usually dies within 15 years of diagnosis. Approximately 1 in 25,000 Caucasians have this disease. Huntington's disease has not been associated with any other disease, now or in the past. Why might natural selection not have eliminated such a deleterious allele from the ...
Hi. I'm Dr Karen Anderson. I'm the director of the Huntington's Disease Care, Education and Research Center at Georgetown MedStar University Hospital. Today we're going to talk about Huntington disease and the apathy and irritability-aggression conundrum. It is an interesting thing in Huntingto...
The experience of children who are raised in a family where a parent has Huntington's Disease (HD) is complex. The purpose of this project was to explore the resiliency of those who were raised in a family with a parent who had HD, explore the effect the gender of the child had on ...
Predictive testing for Huntington disease (HD) in 25% at-risk individuals is testing with full knowledge, and sometimes assuming, that the parent does not want to know his status. The goal of this study was to understand: (1) the differences in the motivation between 25% and 50% at-risk...
This paper recognizes the complexity of the debate on informed consent and discusses the importance of the ongoing process of consent for people affected by Huntington's disease (HD). Although written information may not be the most appropriate form of obtaining informed consent in qualitative researc...
Huntington's Disease (HD) is a late-onset and progressive neurodegenerative disease of the central nervous system with autosomal dominant inheritance. The prevalence of the disease is about 1/100 000 among individuals of European descent. The clinical symptoms of HD involve motor dysfunction, ...
Rosenfeld A ( 1984 ) At risk for Huntington's disease: Who should known what and when? Hast Cent Report 14 : 3 : 5 – 8 .Rosenfeld A (1984) At risk for Huntington's disease: who should know what and when? Hastings Cent Rep 14:5-8...
Likewise, well-controlled intervention studies are often impractical in the setting of established neurodegenerative disease. It is this that makes understanding sleep and circadian abnormalities in Huntington's disease (HD) important: as a monogenic fully penetrant neurodegenerative condition presenting in ...