On a side note, GDSC screen also included many therapeutic reagents currently used for the treatment of human cancers, such as paclitaxel, docetaxel, cisplatin, etc. None of these reagents have a growth inhibitory bias against LKB1-mutant cancer cell lines at statistical significant level. Hence,...
Preclinical activity of HER2-selective tyrosine kinase inhibitor tucatinib as a single agent or in combination with trastuzumab or docetaxel in solid tumor models Mol Canc Therapeut, 19 (4) (Apr 2020), pp. 976-987 CrossrefView in ScopusGoogle Scholar [18] R.K. Murthy, S. Loi, A. Okine...
Meta-analysis of docetaxel-based doublet versus docetaxel alone as second-line treatment for advanced non-small-cell lung cancer. Cancer Chemother Pharmacol. 2012;69(1):99–106. 33. Qi WX, Tang LN, He AN, Shen Z, Yao Y. The role of vandetanib in the second-line treatment for advanced...
For metastatic castration-resistant PCa (mCRPC), Docetaxel, a taxane chemotherapy, was the first drug to be approved in 2004, which was followed by another taxane chemotherapy, Cabazitaxel. In 2010, the FDA approved in the United States Sipuleucel-T, a vaccine therapy targeting prostatic acid ...