Botulinum neurotoxins (BoNTs) are the most potent toxins known and are used to treat an increasing number of medical disorders. All BoNTs are naturally co-expressed with a protective partner protein (NTNH) with which they form a 300 kDa complex, to re
This imbalance could lead to selective pressure on proteins that use a lot of asparagine in their sequences and be beneficial in certain environments or under certain conditions. By elucidating the mechanisms underlying this relationship, we begin to better understand the evolution of Plasmodium ...