The child quickly become frustrated – for example, when something does not go well. The child needs a great deal of support from adults (…) We had speculated that Quin’s personality was coming to the fore when she started throwing tantrums shortly after age two. She was previously a fus...
Importantly, the sexually dimorphic brain, similar to most sex differences, does not fall into a hard binary readout—but rather is on a continuum or spectrum with each cell and each brain region comprised of varying degrees of 'male' and 'female' (Hines, 2005; Joel and McCarthy, 2016)....
The inclusion of sex as a biological variable in research is absolutely essential for improving our understanding of disease mechanisms contributing to risk and resilience. Studies focusing on examining sex differences have demonstrated across many level
Mundy P, Neal R: Neural plasticity, joint attention and a transactional social-orienting model of autism. International Review of Research in Mental Retardation. Edited by: Glidden L. 2001, Academic, New York, 139-168. Google Scholar Chevallier C, Grèzes J, Molesworth C, Berthoz S, Happ...
Given the importance of the combination of both mitochondrial dysfunction and alpha-synuclein pathology (Fig. 2), the chicken-and-egg question in PD pathogenesis is: does alpha-synuclein pathology form due to mitochondrial dysfunction (Fig. 2B), or is mitochondrial damage the consequence of alpha-...
The consumption of nuts does not result in a higher body weight; possible energy regulatory mechanisms include a decrease in subsequent energy intake and an increase in energy expenditure. This research aimed to explore how tree nut and peanut consumption affected energy intake, compensation, and exp...
This emphasizes the importance of host cell polarity regulation to the replication strategy of the virus. The majority of tumor viruses exhibit long-term persistent infections in the host, infecting precursor cells and using the cellular differentiation program for their replication. Examples include B-...
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Macroelectrodes which exhibit high-charge/phase and low-charge density thresholds; they are typically placed on the surface of the target tissue and have a geometric surface area (GSA) larger than 100.000 μm2 [35]. Conversely, microelectrodes exhibit low-charge/phase thresholds and high-...
While astrocyte-to-neuron (AtN) reprogramming holds great promise in regenerative medicine, the molecular mechanisms that govern this unique biological process remain elusive. To understand the function of miRNAs during the AtN reprogramming process, we